AmiGO 2: Term Details for "Rab geranylgeranyltransferase activity" (GO:0004663)

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Term Information

Accession: GO:0004663
Name: Rab geranylgeranyltransferase activity
Ontology: molecular_function
Synonyms: GGTase-II activity, GGTaseII activity, Rab-protein geranylgeranyltransferase activity, RabGGTase activity, geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity, protein geranylgeranyltransferase type II activity, type II protein geranyl-geranyltransferase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. Source: PMID:8621375, GOC:mah, EC:2.5.1.60
Comment: None
History: See term history for GO:0004663 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Rab geranylgeranyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to Rab geranylgeranyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Rab geranylgeranyltransferase activity (excluding "regulates").