AmiGO 2: Term Details for "prostaglandin-endoperoxide synthase activity" (GO:0004666)

Accession: GO:0004666
Name: prostaglandin-endoperoxide synthase activity
Ontology: molecular_function
Synonyms: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity, (PG)H synthase activity, PG synthetase activity, fatty acid cyclooxygenase activity, prostaglandin G/H synthase activity, prostaglandin endoperoxide synthetase activity, prostaglandin synthase activity, prostaglandin synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. Source: EC:1.14.99.1
Comment: None
History: See term history for GO:0004666 at QuickGO
Chem. react.: has participant arachidonate; has participant hydrogen acceptor; has participant hydrogen donor; has participant dioxygen; has participant prostaglandin H2(1-); has participant water
Subset: None
Related: Link to all genes and gene products annotated to prostaglandin-endoperoxide synthase activity (excluding "regulates").; Link to all direct and indirect annotations to prostaglandin-endoperoxide synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for prostaglandin-endoperoxide synthase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
prostaglandin-endoperoxide synthase activity	RO:0000057	arachidonate (CHEBI:32395)
prostaglandin-endoperoxide synthase activity	RO:0000057	hydrogen acceptor (CHEBI:13193)
prostaglandin-endoperoxide synthase activity	RO:0000057	hydrogen donor (CHEBI:17499)
prostaglandin-endoperoxide synthase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
prostaglandin-endoperoxide synthase activity	RO:0000057	dioxygen (CHEBI:15379)
prostaglandin-endoperoxide synthase activity	RO:0000057	prostaglandin H2(1-) (CHEBI:57405)
prostaglandin-endoperoxide synthase activity	RO:0000057	water (CHEBI:15377)

subject	relation	object
positive regulation of prostaglandin-endoperoxide synthase activity (GO:0060585)	RO:0002213	prostaglandin-endoperoxide synthase activity
regulation of prostaglandin-endoperoxide synthase activity (GO:0060584)	RO:0002211	prostaglandin-endoperoxide synthase activity