AmiGO 2: Term Details for "myosin light chain kinase activity" (GO:0004687)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0004687
Name: myosin light chain kinase activity
Ontology: molecular_function
Synonyms: myosin-light-chain kinase activity, ATP:myosin-light-chain O-phosphotransferase activity, MLCK, MLCkase activity, STK18, calcium/calmodulin-dependent myosin light chain kinase activity, myosin kinase activity, myosin light chain protein kinase activity, myosin light-chain kinase (phosphorylating), myosin light-chain kinase (phosphorylating) activity, myosin light-chain kinase activity, smooth-muscle-myosin-light-chain kinase activity, ATP:myosin-light-chain O-phosphotransferase, myosin light-chain kinase
Alternate IDs: None
Definition: Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate. Source: EC:2.7.11.18
Comment: None
History: See term history for GO:0004687 at QuickGO
Chem. react.: has participant L-serine residue; has participant ATP(4-); has participant O-phospho-L-serine(2-) residue; has participant hydron; has participant ADP(3-)
Subset: None
Related: Link to all genes and gene products annotated to myosin light chain kinase activity (excluding "regulates").; Link to all direct and indirect annotations to myosin light chain kinase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for myosin light chain kinase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0140096 catalytic activity, acting on a protein
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004687 myosin light chain kinase activity
GO:0035506 negative regulation of myosin light chain kinase activity
GO:0035505 positive regulation of myosin light chain kinase activity
GO:0035504 regulation of myosin light chain kinase activity

Parents of myosin light chain kinase activity (GO:0004687)

subject	relation	object
myosin light chain kinase activity	is_a	protein serine/threonine kinase activity (GO:0004674)
myosin light chain kinase activity	RO:0000057	L-serine residue (CHEBI:29999)
myosin light chain kinase activity	RO:0000057	ATP(4-) (CHEBI:30616)
myosin light chain kinase activity	RO:0000057	O-phospho-L-serine(2-) residue (CHEBI:83421)
myosin light chain kinase activity	RO:0000057	hydron (CHEBI:15378)
myosin light chain kinase activity	RO:0000057	ADP(3-) (CHEBI:456216)

Children of myosin light chain kinase activity (GO:0004687)

subject	relation	object
regulation of myosin light chain kinase activity (GO:0035504)	RO:0002211	myosin light chain kinase activity
negative regulation of myosin light chain kinase activity (GO:0035506)	RO:0002212	myosin light chain kinase activity
positive regulation of myosin light chain kinase activity (GO:0035505)	RO:0002213	myosin light chain kinase activity

EC: 2.7.11.18
MetaCyc: 2.7.11.18-RXN
Reactome: R-HSA-5668978; R-HSA-445813
RHEA: 22004