AmiGO 2: Term Details for "protein tyrosine kinase activity" (GO:0004713)

Term Information

Accession: GO:0004713
Name: protein tyrosine kinase activity
Ontology: molecular_function
Synonyms: protein-tyrosine kinase activity
Alternate IDs: GO:0004718
Definition: Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. Source: RHEA:10596
Comment: None
History: See term history for GO:0004713 at QuickGO
Chem. react.: has participant L-tyrosine residue; has participant L-tyrosine-O-phosphate(2-) residue; has participant ADP(3-); has participant ATP(4-); has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to protein tyrosine kinase activity (excluding "regulates").; Link to all direct and indirect annotations to protein tyrosine kinase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for protein tyrosine kinase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0140096 catalytic activity, acting on a protein
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0140801 histone H2AXY142 kinase activity
GO:0035401 histone H3Y41 kinase activity
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0061097 regulation of protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity

Parents of protein tyrosine kinase activity (GO:0004713)

subject	relation	object
protein tyrosine kinase activity	RO:0000057	L-tyrosine residue (CHEBI:46858)
protein tyrosine kinase activity	is_a	protein kinase activity (GO:0004672)
protein tyrosine kinase activity	RO:0000057	L-tyrosine-O-phosphate(2-) residue (CHEBI:82620)
protein tyrosine kinase activity	RO:0000057	ADP(3-) (CHEBI:456216)
protein tyrosine kinase activity	RO:0000057	ATP(4-) (CHEBI:30616)
protein tyrosine kinase activity	RO:0000057	hydron (CHEBI:15378)

Children of protein tyrosine kinase activity (GO:0004713)

subject	relation	object
non-membrane spanning protein tyrosine kinase activity (GO:0004715)	is_a	protein tyrosine kinase activity
histone H2AXY142 kinase activity (GO:0140801)	is_a	protein tyrosine kinase activity
positive regulation of protein tyrosine kinase activity (GO:0061098)	RO:0002213	protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity (GO:0004714)	is_a	protein tyrosine kinase activity
negative regulation of protein tyrosine kinase activity (GO:0061099)	RO:0002212	protein tyrosine kinase activity
regulation of protein tyrosine kinase activity (GO:0061097)	RO:0002211	protein tyrosine kinase activity
protein tyrosine kinase inhibitor activity (GO:0030292)	RO:0002630	protein tyrosine kinase activity
histone H3Y41 kinase activity (GO:0035401)	is_a	protein tyrosine kinase activity
protein tyrosine kinase activator activity (GO:0030296)	RO:0002629	protein tyrosine kinase activity

EC: 2.7.10.2
Reactome: R-HSA-9673756; R-HSA-9732738; R-HSA-8875817; R-HSA-9604767; R-HSA-9698003; R-HSA-182969; R-HSA-9698005; R-HSA-2454208; R-HSA-9699578; R-HSA-5654605; R-HSA-5357429; R-HSA-9666425; R-HSA-5654607; R-HSA-9706344; R-HSA-170991; R-HSA-2029984; R-HSA-8876230; R-HSA-5655268; R-HSA-9606159; R-HSA-2201322; R-HSA-2029989; R-HSA-1247844; R-HSA-9624014; R-HSA-9026890; R-HSA-202245; R-HSA-170070; R-HSA-377640; R-HSA-1524186; R-HSA-202248; R-HSA-2012073; R-HSA-2671829; R-HSA-418872; R-HSA-9034814; R-HSA-452097; R-HSA-9033284; R-HSA-68954; R-HSA-9026510; R-HSA-6784006; R-HSA-1250315; R-HSA-9726848; R-HSA-2424487; R-HSA-1671691; R-HSA-2424486; R-HSA-177934; R-HSA-1169421; R-HSA-177937; R-HSA-202233; R-HSA-212710; R-HSA-5607750; R-HSA-2424484; R-HSA-5621370; R-HSA-354073; R-HSA-2404193; R-HSA-190326; R-HSA-9831136; R-HSA-5654149; R-HSA-9669911; R-HSA-8937728; R-HSA-9664588; R-HSA-5683930; R-HSA-9026502; R-HSA-4093332; R-HSA-6806974; R-HSA-1433488; R-HSA-5654397; R-HSA-5655243; R-HSA-5621363; R-HSA-5607745; R-HSA-443817; R-HSA-8848436; R-HSA-9018572; R-HSA-9603420; R-HSA-2404199; R-HSA-432129; R-HSA-5654151; R-HSA-9634390; R-HSA-9032854; R-HSA-1839098; R-HSA-205289; R-HSA-3928594; R-HSA-9011241; R-HSA-8853325; R-HSA-8857925; R-HSA-909730; R-HSA-2395439; R-HSA-909732; R-HSA-9027272; R-HSA-8937844; R-HSA-5621355; R-HSA-9027273; R-HSA-2586553; R-HSA-2586555; R-HSA-5654147; R-HSA-418859; R-HSA-9021609; R-HSA-389159; R-HSA-202216; R-HSA-210872; R-HSA-171011; R-HSA-8876948; R-HSA-202165; R-HSA-2730858; R-HSA-5654407; R-HSA-5218806; R-HSA-4420206; R-HSA-9842648; R-HSA-5218809; R-HSA-5654408; R-HSA-3928627; R-HSA-8849102; R-HSA-8964242; R-HSA-9700164; R-HSA-2730860; R-HSA-2033485; R-HSA-2730862; R-HSA-873919; R-HSA-9700168; R-HSA-5218812; R-HSA-9842651; R-HSA-391866; R-HSA-2033486; R-HSA-391865; R-HSA-873918; R-HSA-5654653; R-HSA-202168; R-HSA-1888198; R-HSA-112333; R-HSA-452100; R-HSA-8849463; R-HSA-429441; R-HSA-1839110; R-HSA-1839112; R-HSA-419646; R-HSA-2671742; R-HSA-2454239; R-HSA-5654634; R-HSA-9664278; R-HSA-183058; R-HSA-9029151; R-HSA-8848124; R-HSA-8848005; R-HSA-190385; R-HSA-8851890; R-HSA-9029155; R-HSA-190388; R-HSA-2730851; R-HSA-2396594; R-HSA-9701488; R-HSA-5686587; R-HSA-982807; R-HSA-429449; R-HSA-3928610; R-HSA-373750; R-HSA-8874080; R-HSA-8874082; R-HSA-389083; R-HSA-5690702; R-HSA-9028728; R-HSA-389086; R-HSA-9032426; R-HSA-2730833; R-HSA-1250348; R-HSA-5654628; R-HSA-2395801; R-HSA-1225960; R-HSA-3928604; R-HSA-9625487; R-HSA-373747; R-HSA-9613023; R-HSA-9664275; R-HSA-2730843; R-HSA-5654631; R-HSA-8874078; R-HSA-389762; R-HSA-5655284; R-HSA-9032532; R-HSA-9034714; R-HSA-8983872; R-HSA-9673761; R-HSA-391156; R-HSA-186786; R-HSA-2012087; R-HSA-374701; R-HSA-1225952; R-HSA-5655278; R-HSA-9664261; R-HSA-2671850; R-HSA-8876246; R-HSA-9606163; R-HSA-2012082; R-HSA-5655270; R-HSA-9706350; R-HSA-9606162; R-HSA-114600; R-HSA-8848726; R-HSA-4420128; R-HSA-8956659; R-HSA-8848606; R-HSA-1433418; R-HSA-9674567; R-HSA-983703; R-HSA-1248655; R-HSA-399947; R-HSA-5218851; R-HSA-1433542; R-HSA-399946; R-HSA-5654575; R-HSA-8848975; R-HSA-5655301; R-HSA-983707; R-HSA-983709; R-HSA-9674558; R-HSA-1295609; R-HSA-6790087; R-HSA-2730888; R-HSA-4420117; R-HSA-1251922; R-HSA-5624486; R-HSA-5637796; R-HSA-399934; R-HSA-9669890; R-HSA-434836; R-HSA-5637795; R-HSA-2130194; R-HSA-2029459; R-HSA-8857555; R-HSA-4420121; R-HSA-354124; R-HSA-879925; R-HSA-9700193; R-HSA-2029453; R-HSA-9024726; R-HSA-9026464; R-HSA-2038944; R-HSA-5654545; R-HSA-8847977; R-HSA-8855237; R-HSA-9842666; R-HSA-5654428; R-HSA-9842667; R-HSA-5218828; R-HSA-1470009; R-HSA-2023460; R-HSA-3928648; R-HSA-1982066; R-HSA-5218830; R-HSA-9700186; R-HSA-2730882; R-HSA-2730884; R-HSA-2029449; R-HSA-2730886; R-HSA-452122; R-HSA-372693; R-HSA-9700181; R-HSA-9665704; R-HSA-9034875; R-HSA-202291; R-HSA-9665705; R-HSA-202174; R-HSA-9665709; R-HSA-9703437; R-HSA-508282; R-HSA-2033488; R-HSA-5654655; R-HSA-9612996; R-HSA-9665389; R-HSA-9703438; R-HSA-1433506; R-HSA-5654418; R-HSA-9027425; R-HSA-8848818; R-HSA-9664976; R-HSA-9026579; R-HSA-873924; R-HSA-2038387; R-HSA-391871; R-HSA-9612085; R-HSA-451942; R-HSA-879907; R-HSA-9700175; R-HSA-879909; R-HSA-8964252; R-HSA-9665032; R-HSA-5218820; R-HSA-2023455; R-HSA-201521; R-HSA-912629; R-HSA-69195; R-HSA-9700171; R-HSA-873922; R-HSA-1307963; R-HSA-2033490; R-HSA-1168394; R-HSA-9680248; R-HSA-3928580; R-HSA-909726; R-HSA-9032601; R-HSA-3928583; R-HSA-909729; R-HSA-9006323; R-HSA-8853313; R-HSA-190427; R-HSA-9665411; R-HSA-191636; R-HSA-418163; R-HSA-190429; R-HSA-445091; R-HSA-8851933; R-HSA-2029268; R-HSA-5655341; R-HSA-170156; R-HSA-8848776; R-HSA-9006332; R-HSA-1295540; R-HSA-428888; R-HSA-8849068; R-HSA-8867041; R-HSA-1248694; R-HSA-445084; R-HSA-8942607; R-HSA-8853309; R-HSA-9762209; R-HSA-210291; R-HSA-445085; R-HSA-909718; R-HSA-9672175; R-HSA-8848758; R-HSA-190413; R-HSA-9709918; R-HSA-2197698; R-HSA-2395412; R-HSA-5218640; R-HSA-5218642; R-HSA-1433454; R-HSA-1472121; R-HSA-8875451; R-HSA-2428926; R-HSA-3928578; R-HSA-6784319; R-HSA-9695834; R-HSA-1839065; R-HSA-445076; R-HSA-1839067; R-HSA-9733323; R-HSA-8937807; R-HSA-190408; R-HSA-9712086; R-HSA-202307; R-HSA-8857583; R-HSA-9712085; R-HSA-9037040; R-HSA-1250195; R-HSA-9712087; R-HSA-8848873; R-HSA-9672173; R-HSA-8849042; R-HSA-191062; R-HSA-388831; R-HSA-8948143; R-HSA-9712082; R-HSA-388833; R-HSA-8848077; R-HSA-9670412; R-HSA-9670418; R-HSA-5654578; R-HSA-9012650; R-HSA-9733314; R-HSA-9700647; R-HSA-5654582; R-HSA-1963586; R-HSA-8857577; R-HSA-5654222; R-HSA-5654587; R-HSA-389354; R-HSA-174164; R-HSA-1963581; R-HSA-3215391; R-HSA-1963582; R-HSA-8849032; R-HSA-380780
RHEA: 10596