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protein tyrosine phosphatase activity

Term Information

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Accession
GO:0004725
Name
protein tyrosine phosphatase activity
Ontology
molecular_function
Synonyms
PPT-phosphatase activity, PTP-phosphatase activity, PTPase activity, [phosphotyrosine]protein phosphatase activity, phosphoprotein phosphatase (phosphotyrosine) activity, phosphotyrosine histone phosphatase activity, phosphotyrosine phosphatase activity, phosphotyrosine protein phosphatase activity, phosphotyrosylprotein phosphatase activity, protein phosphotyrosine phosphatase activity, protein-tyrosine-phosphatase activity, protein-tyrosine-phosphate phosphohydrolase activity, tyrosine O-phosphate phosphatase activity, tyrosylprotein phosphatase activity
Alternate IDs
None
Definition
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. Source: EC:3.1.3.48
Comment
None
History
See term history for GO:0004725 at QuickGO
Chem. react.
has participant L-tyrosine residue
has participant hydrogenphosphate
has participant water
has participant L-tyrosine-O-phosphate(2-) residue
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004725 from QuickGO

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Parents of protein tyrosine phosphatase activity (GO:0004725)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein tyrosine phosphatase activity [RO:0000057 relation] RO:0000057  L-tyrosine residue (CHEBI:46858)
protein tyrosine phosphatase activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
protein tyrosine phosphatase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
protein tyrosine phosphatase activity [RO:0000057 relation] RO:0000057  L-tyrosine-O-phosphate(2-) residue (CHEBI:82620)
protein tyrosine phosphatase activity [is_a relation] is_a  phosphoprotein phosphatase activity (GO:0004721)
Children of protein tyrosine phosphatase activity (GO:0004725)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein tyrosine phosphatase complex (GO:1904096) [RO:0002215 relation] RO:0002215  protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity (GO:0005001) [is_a relation] is_a  protein tyrosine phosphatase activity
protein tyrosine phosphatase activity, metal-dependent (GO:0030946) [is_a relation] is_a  protein tyrosine phosphatase activity
prenylated protein tyrosine phosphatase activity (GO:0004727) [is_a relation] is_a  protein tyrosine phosphatase activity
MAP kinase tyrosine phosphatase activity (GO:0033550) [is_a relation] is_a  protein tyrosine phosphatase activity
regulation of protein tyrosine phosphatase activity (GO:1903613) [RO:0002211 relation] RO:0002211  protein tyrosine phosphatase activity
protein tyrosine phosphatase activity, via thiol-phosphate intermediate (GO:0030945) [is_a relation] is_a  protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity (GO:0004726) [is_a relation] is_a  protein tyrosine phosphatase activity
positive regulation of protein tyrosine phosphatase activity (GO:1903615) [RO:0002213 relation] RO:0002213  protein tyrosine phosphatase activity
protein tyrosine phosphatase activator activity (GO:0008160) [RO:0002629 relation] RO:0002629  protein tyrosine phosphatase activity
negative regulation of protein tyrosine phosphatase activity (GO:1903614) [RO:0002212 relation] RO:0002212  protein tyrosine phosphatase activity