AmiGO 2: Term Details for "pseudouridylate synthase activity" (GO:0004730)

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Term Information

Accession: GO:0004730
Name: pseudouridylate synthase activity
Ontology: molecular_function
Synonyms: pseudouridine monophosphate synthase activity, pseudouridine-5'-phosphate glycosidase activity, 5-ribosyluracil 5-phosphate synthetase activity, pseudouridine monophosphate synthetase activity, pseudouridylate synthetase activity, pseudouridylic acid synthetase activity, psiUMP synthetase activity, uracil hydro-lyase (adding D-ribose 5-phosphate), uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming), uracil hydrolyase activity
Alternate IDs: None
Definition: Catalysis of the reaction: D-ribose 5-phosphate + uracil = H2O + pseudouridine 5'-phosphate. Source: EC:4.2.1.70, RHEA:18337
Comment: Note that this term should not be confused with 'pseudouridine synthase activity ; GO:0009982', which refers to the intramolecular isomerization of uridine to pseudouridine.
History: See term history for GO:0004730 at QuickGO
Chem. react.: has participant uracil; has participant water; has participant pseudouridine 5'-phosphate(2-); has participant D-ribofuranose 5-phosphate(2-)
Subset: None
Related: Link to all genes and gene products annotated to pseudouridylate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to pseudouridylate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for pseudouridylate synthase activity (excluding "regulates").

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0043170 macromolecule metabolic process
GO:0003674 molecular_function
GO:0006139 nucleobase-containing compound metabolic process
GO:0003824 catalytic activity
GO:0090304 nucleic acid metabolic process
GO:0016829 lyase activity
GO:0043412 macromolecule modification
GO:0016070 RNA metabolic process
GO:0016835 carbon-oxygen lyase activity
GO:0009451 RNA modification
GO:0016836 hydro-lyase activity
GO:0001522 pseudouridine synthesis
GO:0004730 pseudouridylate synthase activity

Parents of pseudouridylate synthase activity (GO:0004730)

subject	relation	object
pseudouridylate synthase activity	RO:0000057	uracil (CHEBI:17568)
pseudouridylate synthase activity	RO:0000057	water (CHEBI:15377)
pseudouridylate synthase activity	RO:0000057	pseudouridine 5'-phosphate(2-) (CHEBI:58380)
pseudouridylate synthase activity	RO:0000057	D-ribofuranose 5-phosphate(2-) (CHEBI:78346)
pseudouridylate synthase activity	is_a	hydro-lyase activity (GO:0016836)
pseudouridylate synthase activity	BFO:0000050	pseudouridine synthesis (GO:0001522)

This term has no children.

EC: 4.2.1.70
KEGG_REACTION: R01055
MetaCyc: RXN0-5398
RHEA: 18337