AmiGO 2: Term Details for "pyrimidodiazepine synthase activity" (GO:0004734)

Accession: GO:0004734
Name: pyrimidodiazepine synthase activity
Ontology: molecular_function
Synonyms: PDA synthase activity, pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)
Alternate IDs: None
Definition: Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione. Source: EC:1.5.4.1
Comment: None
History: See term history for GO:0004734 at QuickGO
Chem. react.: has participant glutathione disulfide(2-); has participant 6-acetyl-2-amino-3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one; has participant (R)-dyspropterin; has participant glutathionate(1-); has participant water
Subset: None
Related: Link to all genes and gene products annotated to pyrimidodiazepine synthase activity (excluding "regulates").; Link to all direct and indirect annotations to pyrimidodiazepine synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for pyrimidodiazepine synthase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
pyrimidodiazepine synthase activity	RO:0000057	glutathione disulfide(2-) (CHEBI:58297)
pyrimidodiazepine synthase activity	RO:0000057	6-acetyl-2-amino-3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one (CHEBI:27714)
pyrimidodiazepine synthase activity	RO:0000057	(R)-dyspropterin (CHEBI:136564)
pyrimidodiazepine synthase activity	RO:0000057	glutathionate(1-) (CHEBI:57925)
pyrimidodiazepine synthase activity	RO:0000057	water (CHEBI:15377)
pyrimidodiazepine synthase activity	is_a	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor (GO:0016648)

This term has no children.