AmiGO 2: Term Details for "pyruvate dehydrogenase (acetyl-transferring) activity" (GO:0004739)

Accession: GO:0004739
Name: pyruvate dehydrogenase (acetyl-transferring) activity
Ontology: molecular_function
Synonyms: pyruvate dehydrogenase (lipoamide) activity, PDH, pyruvate dehydrogenase complex activity, pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating), pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity, MtPDC (mitochondrial pyruvate dehydogenase complex) activity
Alternate IDs: None
Definition: Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2. Source: EC:1.2.4.1
Comment: None
History: See term history for GO:0004739 at QuickGO
Chem. react.: has participant carbon dioxide; has participant N(6)-[(R)-lipoyl]-L-lysine residue; has participant N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysine residue; has participant pyruvate; has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to pyruvate dehydrogenase (acetyl-transferring) activity (excluding "regulates").; Link to all direct and indirect annotations to pyruvate dehydrogenase (acetyl-transferring) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for pyruvate dehydrogenase (acetyl-transferring) activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
pyruvate dehydrogenase (acetyl-transferring) activity	is_a	pyruvate dehydrogenase activity (GO:0004738)
pyruvate dehydrogenase (acetyl-transferring) activity	RO:0000057	carbon dioxide (CHEBI:16526)
pyruvate dehydrogenase (acetyl-transferring) activity	RO:0000057	N(6)-[(R)-lipoyl]-L-lysine residue (CHEBI:83099)
pyruvate dehydrogenase (acetyl-transferring) activity	RO:0000057	N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysine residue (CHEBI:83111)
pyruvate dehydrogenase (acetyl-transferring) activity	is_a	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624)
pyruvate dehydrogenase (acetyl-transferring) activity	RO:0000057	pyruvate (CHEBI:15361)
pyruvate dehydrogenase (acetyl-transferring) activity	RO:0000057	hydron (CHEBI:15378)

This term has no children.