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ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

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Accession
GO:0004748
Name
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Ontology
molecular_function
Synonyms
2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity, 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity
Alternate IDs
GO:0016959, GO:0016960, GO:0016961
Definition
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. Source: EC:1.17.4.1
Comment
When thioredoxin is substituted for glutaredoxin in the reaction, annotate instead to 'ribonucleoside-diphosphate reductase, glutaredoxin disulfide as acceptor ; GO:0036175'.
History
See term history for GO:0004748 at QuickGO
Chem. react.
has participant water
has participant L-cysteine residue
has participant nucleoside 5'-diphosphate(3-)
has participant 2'-deoxyribonucleoside 5'-diphosphate(3-)
has participant L-cystine residue
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (GO:0004748)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [RO:0000057 relation] RO:0000057  L-cysteine residue (CHEBI:29950)
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [RO:0000057 relation] RO:0000057  nucleoside 5'-diphosphate(3-) (CHEBI:57930)
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [is_a relation] is_a  ribonucleoside-diphosphate reductase activity (GO:0061731)
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [RO:0000057 relation] RO:0000057  2'-deoxyribonucleoside 5'-diphosphate(3-) (CHEBI:73316)
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [RO:0000057 relation] RO:0000057  L-cystine residue (CHEBI:50058)
Children of ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (GO:0004748)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
UDP reductase activity (GO:0051062) [is_a relation] is_a  ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
CDP reductase activity (GO:0051063) [is_a relation] is_a  ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ADP reductase activity (GO:0051061) [is_a relation] is_a  ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor