Term Information

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Accession
GO:0004758
Name
serine C-palmitoyltransferase activity
Ontology
molecular_function
Synonyms
3-oxosphinganine synthetase activity, SPT, serine palmitoyltransferase
Alternate IDs
None
Definition
Catalysis of the reaction: L-serine + H+ + palmitoyl-CoA = 3-dehydrosphinganine + CO2 + CoA. Source: EC:2.3.1.50, RHEA:14761
Comment
None
History
See term history for GO:0004758 at QuickGO
Chem. react.
has participant palmitoyl-CoA(4-)
has participant hydron
has participant L-serine zwitterion
has participant 3-dehydrosphinganinium(1+)
has participant coenzyme A(4-)
has participant carbon dioxide
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004758 from QuickGO

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Parents of serine C-palmitoyltransferase activity (GO:0004758)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
serine C-palmitoyltransferase activity [is_a relation] is_a  C-palmitoyltransferase activity (GO:0016454)
serine C-palmitoyltransferase activity [RO:0000057 relation] RO:0000057  palmitoyl-CoA(4-) (CHEBI:57379)
serine C-palmitoyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
serine C-palmitoyltransferase activity [RO:0000057 relation] RO:0000057  L-serine zwitterion (CHEBI:33384)
serine C-palmitoyltransferase activity [RO:0000057 relation] RO:0000057  3-dehydrosphinganinium(1+) (CHEBI:58299)
serine C-palmitoyltransferase activity [RO:0000057 relation] RO:0000057  coenzyme A(4-) (CHEBI:57287)
serine C-palmitoyltransferase activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
Children of serine C-palmitoyltransferase activity (GO:0004758)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of serine C-palmitoyltransferase activity (GO:1904222) [RO:0002213 relation] RO:0002213  serine C-palmitoyltransferase activity
negative regulation of serine C-palmitoyltransferase activity (GO:1904221) [RO:0002212 relation] RO:0002212  serine C-palmitoyltransferase activity
endoplasmic reticulum palmitoyltransferase complex (GO:0031211) [RO:0002215 relation] RO:0002215  serine C-palmitoyltransferase activity
regulation of serine C-palmitoyltransferase activity (GO:1904220) [RO:0002211 relation] RO:0002211  serine C-palmitoyltransferase activity
homodimeric serine palmitoyltransferase complex (GO:0002179) [RO:0002215 relation] RO:0002215  serine C-palmitoyltransferase activity
EC
2.3.1.50
KEGG_REACTION
R01281
MetaCyc
SERINE-C-PALMITOYLTRANSFERASE-RXN
Reactome
R-HSA-428127
RHEA
14761