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sphingomyelin phosphodiesterase activity

Term Information

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Accession
GO:0004767
Name
sphingomyelin phosphodiesterase activity
Ontology
molecular_function
Synonyms
sphingomyelinase activity, sphingomyelin cholinephosphohydrolase activity
Alternate IDs
GO:0030230, GO:0030231
Definition
Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+. Source: EC:3.1.4.12, RHEA:19253
Comment
None
History
See term history for GO:0004767 at QuickGO
Chem. react.
has participant sphingomyelin d18:1
has participant N-acylsphingosine
has participant choline phosphate(1-)
has participant water
has participant hydron
Subset
goslim_chembl
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of sphingomyelin phosphodiesterase activity (GO:0004767)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sphingomyelin phosphodiesterase activity [RO:0000057 relation] RO:0000057  sphingomyelin d18:1 (CHEBI:17636)
sphingomyelin phosphodiesterase activity [RO:0000057 relation] RO:0000057  N-acylsphingosine (CHEBI:52639)
sphingomyelin phosphodiesterase activity [is_a relation] is_a  phospholipase activity (GO:0004620)
sphingomyelin phosphodiesterase activity [RO:0000057 relation] RO:0000057  choline phosphate(1-) (CHEBI:295975)
sphingomyelin phosphodiesterase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
sphingomyelin phosphodiesterase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
sphingomyelin phosphodiesterase activity [is_a relation] is_a  phosphoric diester hydrolase activity (GO:0008081)
Children of sphingomyelin phosphodiesterase activity (GO:0004767)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
sphingomyelin phosphodiesterase activator activity (GO:0016230) [RO:0002629 relation] RO:0002629  sphingomyelin phosphodiesterase activity
acid sphingomyelin phosphodiesterase activity (GO:0061750) [is_a relation] is_a  sphingomyelin phosphodiesterase activity
neutral sphingomyelin phosphodiesterase activity (GO:0061751) [is_a relation] is_a  sphingomyelin phosphodiesterase activity