AmiGO 2: Term Details for "thymidylate synthase activity" (GO:0004799)

Accession: GO:0004799
Name: thymidylate synthase activity
Ontology: molecular_function
Synonyms: 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity, TMP synthetase activity, dTMP synthase activity, methylenetetrahydrofolate:dUMP C-methyltransferase activity, thymidylate synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. Source: RHEA:12104, EC:2.1.1.45
Comment: None
History: See term history for GO:0004799 at QuickGO
Chem. react.: has participant dUMP(2-); has participant dTMP(2-); has participant (6R)-5,10-methylenetetrahydrofolate(2-); has participant dihydrofolate(2-)
Subset: None
Related: Link to all genes and gene products annotated to thymidylate synthase activity (excluding "regulates").; Link to all direct and indirect annotations to thymidylate synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for thymidylate synthase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
thymidylate synthase activity	is_a	5,10-methylenetetrahydrofolate-dependent methyltransferase activity (GO:0042083)
thymidylate synthase activity	RO:0000057	dUMP(2-) (CHEBI:246422)
thymidylate synthase activity	RO:0000057	dTMP(2-) (CHEBI:63528)
thymidylate synthase activity	RO:0000057	(6R)-5,10-methylenetetrahydrofolate(2-) (CHEBI:15636)
thymidylate synthase activity	RO:0000057	dihydrofolate(2-) (CHEBI:57451)

This term has no children.