AmiGO 2: Term Details for "alanine-tRNA ligase activity" (GO:0004813)

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Term Information

Accession: GO:0004813
Name: alanine-tRNA ligase activity
Ontology: molecular_function
Synonyms: alanyl-tRNA synthetase activity, Ala-tRNA synthetase activity, AlaRS, L-alanine:tRNAAla ligase (AMP-forming), alanine tRNA synthetase activity, alanine transfer RNA synthetase activity, alanine translase activity, alanine-transfer RNA ligase activity, alanyl-transfer RNA synthetase activity, alanyl-transfer ribonucleate synthase activity, alanyl-transfer ribonucleate synthetase activity, alanyl-transfer ribonucleic acid synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). Source: EC:6.1.1.7
Comment: None
History: See term history for GO:0004813 at QuickGO
Chem. react.: has participant L-alanine zwitterion; has participant diphosphate(3-); has participant ATP(4-); has participant AMP 3'-end(1-) residue; has participant 3'-(L-alanyl)adenylyl zwitterionic group; has participant adenosine 5'-monophosphate(2-)
Subset: None
Related: Link to all genes and gene products annotated to alanine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations to alanine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for alanine-tRNA ligase activity (excluding "regulates").

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0140098 catalytic activity, acting on RNA
GO:0016874 ligase activity
GO:0140101 catalytic activity, acting on a tRNA
GO:0016875 ligase activity, forming carbon-oxygen bonds
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004813 alanine-tRNA ligase activity

Parents of alanine-tRNA ligase activity (GO:0004813)

subject	relation	object
alanine-tRNA ligase activity	RO:0000057	L-alanine zwitterion (CHEBI:57972)
alanine-tRNA ligase activity	RO:0000057	diphosphate(3-) (CHEBI:33019)
alanine-tRNA ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
alanine-tRNA ligase activity	RO:0000057	AMP 3'-end(1-) residue (CHEBI:78442)
alanine-tRNA ligase activity	is_a	aminoacyl-tRNA ligase activity (GO:0004812)
alanine-tRNA ligase activity	RO:0000057	3'-(L-alanyl)adenylyl zwitterionic group (CHEBI:78497)
alanine-tRNA ligase activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)

This term has no children.

EC: 6.1.1.7
MetaCyc: ALANINE--TRNA-LIGASE-RXN
Reactome: R-HSA-380177; R-HSA-379864
RHEA: 12540