AmiGO 2: Term Details for "isoleucine-tRNA ligase activity" (GO:0004822)

Accession: GO:0004822
Name: isoleucine-tRNA ligase activity
Ontology: molecular_function
Synonyms: isoleucyl-tRNA synthetase activity, L-isoleucine:tRNAIle ligase (AMP-forming), isoleucine translase activity, isoleucine-tRNA synthetase activity, isoleucine-transfer RNA ligase activity, isoleucyl-transfer RNA synthetase activity, isoleucyl-transfer ribonucleate synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H+. Source: RHEA:11060, EC:6.1.1.5
Comment: None
History: See term history for GO:0004822 at QuickGO
Chem. react.: has participant L-isoleucine zwitterion; has participant ATP(4-); has participant 3'-(L-isoleucyl)adenylyl zwitterionic group; has participant adenosine 5'-monophosphate(2-); has participant diphosphate(3-); has participant AMP 3'-end(1-) residue
Subset: None
Related: Link to all genes and gene products annotated to isoleucine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations to isoleucine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for isoleucine-tRNA ligase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
isoleucine-tRNA ligase activity	RO:0000057	L-isoleucine zwitterion (CHEBI:58045)
isoleucine-tRNA ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
isoleucine-tRNA ligase activity	is_a	aminoacyl-tRNA ligase activity (GO:0004812)
isoleucine-tRNA ligase activity	RO:0000057	3'-(L-isoleucyl)adenylyl zwitterionic group (CHEBI:78528)
isoleucine-tRNA ligase activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)
isoleucine-tRNA ligase activity	RO:0000057	diphosphate(3-) (CHEBI:33019)
isoleucine-tRNA ligase activity	RO:0000057	AMP 3'-end(1-) residue (CHEBI:78442)

subject	relation	object
positive regulation of isoleucine-tRNA ligase activity (GO:1905017)	RO:0002213	isoleucine-tRNA ligase activity