AmiGO 2: Term Details for "methionine-tRNA ligase activity" (GO:0004825)

Accession: GO:0004825
Name: methionine-tRNA ligase activity
Ontology: molecular_function
Synonyms: methionyl-tRNA synthetase activity, L-methionine:tRNAMet ligase (AMP-forming), MetRS activity, methionine translase activity, methionyl-transfer RNA synthetase activity, methionyl-transfer ribonucleate synthetase activity, methionyl-transfer ribonucleic acid synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met). Source: EC:6.1.1.10
Comment: None
History: See term history for GO:0004825 at QuickGO
Chem. react.: has participant L-methionine zwitterion; has participant AMP 3'-end(1-) residue; has participant 3'-(L-methionyl)adenylyl zwitterionic group; has participant diphosphate(3-); has participant adenosine 5'-monophosphate(2-); has participant ATP(4-)
Subset: None
Related: Link to all genes and gene products annotated to methionine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations to methionine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for methionine-tRNA ligase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
methionine-tRNA ligase activity	RO:0000057	L-methionine zwitterion (CHEBI:57844)
methionine-tRNA ligase activity	RO:0000057	AMP 3'-end(1-) residue (CHEBI:78442)
methionine-tRNA ligase activity	RO:0000057	3'-(L-methionyl)adenylyl zwitterionic group (CHEBI:78530)
methionine-tRNA ligase activity	RO:0000057	diphosphate(3-) (CHEBI:33019)
methionine-tRNA ligase activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)
methionine-tRNA ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
methionine-tRNA ligase activity	is_a	aminoacyl-tRNA ligase activity (GO:0004812)

subject	relation	object
positive regulation of methionine-tRNA ligase activity (GO:1905020)	RO:0002213	methionine-tRNA ligase activity