AmiGO 2: Term Details for "tyrosine-tRNA ligase activity" (GO:0004831)

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Term Information

Accession: GO:0004831
Name: tyrosine-tRNA ligase activity
Ontology: molecular_function
Synonyms: tyrosyl-tRNA synthetase activity, L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity, L-tyrosine-tRNATyr ligase (AMP-forming), L-tyrosine:tRNATyr ligase (AMP-forming), tyrosine tRNA synthetase activity, tyrosine translase activity, tyrosine-transfer RNA ligase activity, tyrosine-transfer ribonucleate synthetase activity, tyrosyl-tRNA ligase activity, tyrosyl-transfer RNA synthetase activity, tyrosyl-transfer ribonucleate synthetase activity, tyrosyl-transfer ribonucleic acid synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H+. Source: EC:6.1.1.1, RHEA:10220
Comment: None
History: See term history for GO:0004831 at QuickGO
Chem. react.: has participant L-tyrosine zwitterion; has participant adenosine 5'-monophosphate(2-); has participant 3'-(L-tyrosyl)adenylyl(1-) group; has participant AMP 3'-end(1-) residue; has participant hydron; has participant ATP(4-); has participant diphosphate(3-)
Subset: None
Related: Link to all genes and gene products annotated to tyrosine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations to tyrosine-tRNA ligase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for tyrosine-tRNA ligase activity (excluding "regulates").

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0140098 catalytic activity, acting on RNA
GO:0016874 ligase activity
GO:0140101 catalytic activity, acting on a tRNA
GO:0016875 ligase activity, forming carbon-oxygen bonds
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity

Parents of tyrosine-tRNA ligase activity (GO:0004831)

subject	relation	object
tyrosine-tRNA ligase activity	is_a	aminoacyl-tRNA ligase activity (GO:0004812)
tyrosine-tRNA ligase activity	RO:0000057	L-tyrosine zwitterion (CHEBI:58315)
tyrosine-tRNA ligase activity	RO:0000057	adenosine 5'-monophosphate(2-) (CHEBI:456215)
tyrosine-tRNA ligase activity	RO:0000057	3'-(L-tyrosyl)adenylyl(1-) group (CHEBI:78536)
tyrosine-tRNA ligase activity	RO:0000057	AMP 3'-end(1-) residue (CHEBI:78442)
tyrosine-tRNA ligase activity	RO:0000057	hydron (CHEBI:15378)
tyrosine-tRNA ligase activity	RO:0000057	ATP(4-) (CHEBI:30616)
tyrosine-tRNA ligase activity	RO:0000057	diphosphate(3-) (CHEBI:33019)

This term has no children.

EC: 6.1.1.1
KEGG_REACTION: R02918
MetaCyc: TYROSINE--TRNA-LIGASE-RXN
Reactome: R-HSA-379980; R-HSA-380170
RHEA: 10220