AmiGO 2: Term Details for "tryptophan 2,3-dioxygenase activity" (GO:0004833)

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Term Information

Accession: GO:0004833
Name: tryptophan 2,3-dioxygenase activity
Ontology: molecular_function
Synonyms: indoleamine-pyrrole 2,3-dioxygenase activity, L-tryptophan 2,3-dioxygenase activity, L-tryptophan pyrrolase activity, L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing), TDO, tryptamin 2,3-dioxygenase activity, tryptamine 2,3-dioxygenase activity, indolamine 2,3-dioxygenase activity, tryptophan oxygenase activity, tryptophan peroxidase activity, tryptophan pyrrolase activity
Alternate IDs: GO:0004426
Definition: Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine. Source: EC:1.13.11.11
Comment: None
History: See term history for GO:0004833 at QuickGO
Chem. react.: has participant N-formyl-L-kynurenine zwitterion; has participant L-tryptophan zwitterion; has participant dioxygen
Subset: None
Related: Link to all genes and gene products annotated to tryptophan 2,3-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations to tryptophan 2,3-dioxygenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for tryptophan 2,3-dioxygenase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0051213 dioxygenase activity
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0004833 tryptophan 2,3-dioxygenase activity

Parents of tryptophan 2,3-dioxygenase activity (GO:0004833)

subject	relation	object
tryptophan 2,3-dioxygenase activity	RO:0000057	N-formyl-L-kynurenine zwitterion (CHEBI:58629)
tryptophan 2,3-dioxygenase activity	RO:0000057	L-tryptophan zwitterion (CHEBI:57912)
tryptophan 2,3-dioxygenase activity	is_a	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702)
tryptophan 2,3-dioxygenase activity	RO:0000057	dioxygen (CHEBI:15379)

This term has no children.

EC: 1.13.11.11
MetaCyc: TRYPTOPHAN-23-DIOXYGENASE-RXN
Reactome: R-HSA-71188; R-HSA-888614; R-HSA-198563
RHEA: 24536