AmiGO 2: Term Details for "uroporphyrinogen-III synthase activity" (GO:0004852)

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Term Information

Accession: GO:0004852
Name: uroporphyrinogen-III synthase activity
Ontology: molecular_function
Synonyms: URO-synthase activity, hydroxymethylbilane hydro-lyase (cyclizing) activity, hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming), porphobilinogenase activity, uroporphyrinogen III cosynthase activity, uroporphyrinogen isomerase activity, uroporphyrinogen-III cosynthase activity, uroporphyrinogen-III cosynthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: hydroxymethylbilane = H2O + uroporphyrinogen III. Source: EC:4.2.1.75, RHEA:18965
Comment: None
History: See term history for GO:0004852 at QuickGO
Chem. react.: has participant uroporphyrinogen III(8-); has participant preuroporphyrinogen(8-); has participant water
Subset: None
Related: Link to all genes and gene products annotated to uroporphyrinogen-III synthase activity (excluding "regulates").; Link to all direct and indirect annotations to uroporphyrinogen-III synthase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for uroporphyrinogen-III synthase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016835 carbon-oxygen lyase activity
GO:0016836 hydro-lyase activity
GO:0004852 uroporphyrinogen-III synthase activity

Parents of uroporphyrinogen-III synthase activity (GO:0004852)

subject	relation	object
uroporphyrinogen-III synthase activity	RO:0000057	uroporphyrinogen III(8-) (CHEBI:57308)
uroporphyrinogen-III synthase activity	is_a	hydro-lyase activity (GO:0016836)
uroporphyrinogen-III synthase activity	RO:0000057	preuroporphyrinogen(8-) (CHEBI:57845)
uroporphyrinogen-III synthase activity	RO:0000057	water (CHEBI:15377)

This term has no children.

EC: 4.2.1.75
KEGG_REACTION: R03165
MetaCyc: UROGENIIISYN-RXN
Reactome: R-HSA-189488
RHEA: 18965