Term Information

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Accession
GO:0005024
Name
transforming growth factor beta receptor activity
Ontology
molecular_function
Synonyms
TGF-beta receptor activity, TGFbeta receptor activity, TGFbeta-activated receptor activity, TGFbetaR, transforming growth factor beta-activated receptor activity
Alternate IDs
None
Definition
Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Source: GOC:signaling, GOC:mah
Comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
History
See term history for GO:0005024 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0005024 from QuickGO

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Parents of transforming growth factor beta receptor activity (GO:0005024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transforming growth factor beta receptor activity [RO:0004009 relation] RO:0004009  TGF-beta (PR:000000046)
transforming growth factor beta receptor activity [is_a relation] is_a  transmembrane receptor protein serine/threonine kinase activity (GO:0004675)
Children of transforming growth factor beta receptor activity (GO:0005024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transforming growth factor beta receptor activity, type I (GO:0005025) [is_a relation] is_a  transforming growth factor beta receptor activity
transforming growth factor beta receptor activity, type II (GO:0005026) [is_a relation] is_a  transforming growth factor beta receptor activity
transforming growth factor beta receptor activity, type III (GO:0070123) [is_a relation] is_a  transforming growth factor beta receptor activity
transforming growth factor beta ligand-receptor complex (GO:0070021) [RO:0002215 relation] RO:0002215  transforming growth factor beta receptor activity
None.