AmiGO 2: Term Details for "inositol 1,4,5-trisphosphate-gated calcium channel activity" (GO:0005220)

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Term Information

Accession: GO:0005220
Name: inositol 1,4,5-trisphosphate-gated calcium channel activity
Ontology: molecular_function
Synonyms: IP3 receptor activity, InsP3 receptor, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, inositol-1,4,5-trisphosphate receptor activity
Alternate IDs: GO:0008095
Definition: Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts. Source: GOC:signaling, PMID:8660280, Wikipedia:Inositol_trisphosphate_receptor, GOC:mah, PMID:28416699
Comment: None
History: See term history for GO:0005220 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to inositol 1,4,5-trisphosphate-gated calcium channel activity (excluding "regulates").; Link to all direct and indirect annotations to inositol 1,4,5-trisphosphate-gated calcium channel activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for inositol 1,4,5-trisphosphate-gated calcium channel activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
GO:0008150 biological_process
UBERON:0001062 anatomical entity
GO:0051179 localization
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
CARO:0000003 connected anatomical structure
GO:0051234 establishment of localization
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0003674 molecular_function
GO:0006811 monoatomic ion transport
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0006810 transport
CL:0000000 cell
GO:0007154 cell communication
GO:0110165 cellular anatomical entity
GO:0051716 cellular response to stimulus
GO:0098660 inorganic ion transmembrane transport
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0030001 metal ion transport
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0005215 transporter activity
GO:0006816 calcium ion transport
GO:0015267 channel activity
GO:0098662 inorganic cation transmembrane transport
GO:0022890 inorganic cation transmembrane transporter activity
GO:0005622 intracellular anatomical structure
GO:0098655 monoatomic cation transmembrane transport
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0022803 passive transmembrane transporter activity
GO:0007165 signal transduction
GO:0070588 calcium ion transmembrane transport
GO:0022836 gated channel activity
GO:0035556 intracellular signal transduction
GO:0046873 metal ion transmembrane transporter activity
GO:0005216 monoatomic ion channel activity
GO:0015085 calcium ion transmembrane transporter activity
GO:0141124 intracellular signaling cassette
GO:0022834 ligand-gated channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0005261 monoatomic cation channel activity
GO:0005262 calcium channel activity
GO:0019722 calcium-mediated signaling
GO:0099094 ligand-gated monoatomic cation channel activity
GO:0005217 intracellularly ligand-gated monoatomic ion channel activity
GO:0099604 ligand-gated calcium channel activity
GO:0015278 intracellularly gated calcium channel activity
GO:0005220 inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0098695 inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels
GO:0031586 negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Parents of inositol 1,4,5-trisphosphate-gated calcium channel activity (GO:0005220)

subject	relation	object
inositol 1,4,5-trisphosphate-gated calcium channel activity	is_a	intracellularly gated calcium channel activity (GO:0015278)
inositol 1,4,5-trisphosphate-gated calcium channel activity	BFO:0000051	inositol 1,4,5 trisphosphate binding (GO:0070679)

Children of inositol 1,4,5-trisphosphate-gated calcium channel activity (GO:0005220)

subject	relation	object
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031585)	RO:0002211	inositol 1,4,5-trisphosphate-gated calcium channel activity
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031587)	RO:0002213	inositol 1,4,5-trisphosphate-gated calcium channel activity
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031586)	RO:0002212	inositol 1,4,5-trisphosphate-gated calcium channel activity
inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels (GO:0098695)	is_a	inositol 1,4,5-trisphosphate-gated calcium channel activity

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