AmiGO 2: Term Details for "voltage-gated sodium channel activity" (GO:0005248)

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Term Information

Accession: GO:0005248
Name: voltage-gated sodium channel activity
Ontology: molecular_function
Synonyms: voltage gated sodium channel activity, voltage-dependent sodium channel activity, voltage-gated sodium ion channel activity, voltage-sensitive sodium channel
Alternate IDs: None
Definition: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. Source: GOC:mtg_transport, ISBN:0815340729
Comment: None
History: See term history for GO:0005248 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to voltage-gated sodium channel activity (excluding "regulates").; Link to all direct and indirect annotations to voltage-gated sodium channel activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for voltage-gated sodium channel activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0009987 cellular process
GO:0003674 molecular_function
GO:0006810 transport
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0005215 transporter activity
GO:0098660 inorganic ion transmembrane transport
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0030001 metal ion transport
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0022803 passive transmembrane transporter activity
GO:0015267 channel activity
GO:0098662 inorganic cation transmembrane transport
GO:0022890 inorganic cation transmembrane transporter activity
GO:0098655 monoatomic cation transmembrane transport
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0006814 sodium ion transport
GO:0046873 metal ion transmembrane transporter activity
GO:0005216 monoatomic ion channel activity
GO:0035725 sodium ion transmembrane transport
GO:0005261 monoatomic cation channel activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0005272 sodium channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0101013 mechanosensitive voltage-gated sodium channel activity
GO:1905151 negative regulation of voltage-gated sodium channel activity
GO:1905152 positive regulation of voltage-gated sodium channel activity
GO:1905150 regulation of voltage-gated sodium channel activity
GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0001518 voltage-gated sodium channel complex

Parents of voltage-gated sodium channel activity (GO:0005248)

subject	relation	object
voltage-gated sodium channel activity	is_a	sodium channel activity (GO:0005272)

Children of voltage-gated sodium channel activity (GO:0005248)

subject	relation	object
mechanosensitive voltage-gated sodium channel activity (GO:0101013)	is_a	voltage-gated sodium channel activity
voltage-gated sodium channel complex (GO:0001518)	RO:0002215	voltage-gated sodium channel activity
voltage-gated sodium channel activity involved in cardiac muscle cell action potential (GO:0086006)	is_a	voltage-gated sodium channel activity
negative regulation of voltage-gated sodium channel activity (GO:1905151)	RO:0002212	voltage-gated sodium channel activity
positive regulation of voltage-gated sodium channel activity (GO:1905152)	RO:0002213	voltage-gated sodium channel activity
regulation of voltage-gated sodium channel activity (GO:1905150)	RO:0002211	voltage-gated sodium channel activity

Reactome: R-HSA-5576895