AmiGO 2: Term Details for "P-type sodium:potassium-exchanging transporter activity" (GO:0005391)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0005391
Name: P-type sodium:potassium-exchanging transporter activity
Ontology: molecular_function
Synonyms: P-type sodium:potassium-exchanging ATPase activity, sodium/potassium-exchanging ATPase activity, sodium/potassium-transporting ATPase activity, sodium:potassium exchanging ATPase activity, sodium:potassium-exchanging ATPase activity, Na(+)/K(+)-ATPase activity, Na(+)/K(+)-exchanging ATPase activity, Na+,K+-ATPase activity, Na+/K+-ATPase activity, Na+/K+-exchanging ATPase activity, Na,K-activated ATPase activity, sodium pump
Alternate IDs: None
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in). Source: EC:7.2.2.13
Comment: None
History: See term history for GO:0005391 at QuickGO
Chem. react.: has participant ADP(3-); has participant water; has participant hydrogenphosphate; has participant ATP(4-); has participant potassium(1+); has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to P-type sodium:potassium-exchanging transporter activity (excluding "regulates").; Link to all direct and indirect annotations to P-type sodium:potassium-exchanging transporter activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for P-type sodium:potassium-exchanging transporter activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0008150 biological_process
GO:0003674 molecular_function
GO:0051179 localization
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0005215 transporter activity
GO:0022804 active transmembrane transporter activity
GO:0051234 establishment of localization
GO:0098660 inorganic ion transmembrane transport
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0030001 metal ion transport
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0140657 ATP-dependent activity
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0009987 cellular process
GO:0098662 inorganic cation transmembrane transport
GO:0022890 inorganic cation transmembrane transporter activity
GO:0098655 monoatomic cation transmembrane transport
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0006813 potassium ion transport
GO:0015399 primary active transmembrane transporter activity
GO:0006814 sodium ion transport
GO:0006810 transport
GO:0022853 active monoatomic ion transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
GO:0140358 P-type transmembrane transporter activity
GO:0071805 potassium ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity
GO:0015662 P-type ion transporter activity
GO:0015079 potassium ion transmembrane transporter activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient
GO:0008556 P-type potassium transmembrane transporter activity
GO:0008554 P-type sodium transporter activity
GO:0005391 P-type sodium:potassium-exchanging transporter activity
GO:1903407 negative regulation of P-type sodium:potassium-exchanging transporter activity
GO:0086037 P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential
GO:1903408 positive regulation of P-type sodium:potassium-exchanging transporter activity
GO:1903406 regulation of P-type sodium:potassium-exchanging transporter activity
GO:0005890 sodium:potassium-exchanging ATPase complex

Parents of P-type sodium:potassium-exchanging transporter activity (GO:0005391)

subject	relation	object
P-type sodium:potassium-exchanging transporter activity	RO:0004009	sodium(1+) (CHEBI:29101)
P-type sodium:potassium-exchanging transporter activity	RO:0000057	ADP(3-) (CHEBI:456216)
P-type sodium:potassium-exchanging transporter activity	RO:0000057	water (CHEBI:15377)
P-type sodium:potassium-exchanging transporter activity	BFO:0000050	establishment or maintenance of transmembrane electrochemical gradient (GO:0010248)
P-type sodium:potassium-exchanging transporter activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
P-type sodium:potassium-exchanging transporter activity	RO:0000057	ATP(4-) (CHEBI:30616)
P-type sodium:potassium-exchanging transporter activity	RO:0000057	potassium(1+) (CHEBI:29103)
P-type sodium:potassium-exchanging transporter activity	is_a	P-type potassium transmembrane transporter activity (GO:0008556)
P-type sodium:potassium-exchanging transporter activity	is_a	P-type sodium transporter activity (GO:0008554)
P-type sodium:potassium-exchanging transporter activity	RO:0000057	hydron (CHEBI:15378)

Children of P-type sodium:potassium-exchanging transporter activity (GO:0005391)

subject	relation	object
positive regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903408)	RO:0002213	P-type sodium:potassium-exchanging transporter activity
regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903406)	RO:0002211	P-type sodium:potassium-exchanging transporter activity
P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential (GO:0086037)	is_a	P-type sodium:potassium-exchanging transporter activity
negative regulation of P-type sodium:potassium-exchanging transporter activity (GO:1903407)	RO:0002212	P-type sodium:potassium-exchanging transporter activity
sodium:potassium-exchanging ATPase complex (GO:0005890)	RO:0002215	P-type sodium:potassium-exchanging transporter activity


EC: 7.2.2.13
MetaCyc: 3.6.3.9-RXN
Reactome: R-HSA-936897
RHEA: 18353
TC: 3.A.3.1.1