AmiGO 2: Term Details for "calcium:sodium antiporter activity" (GO:0005432)

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Term Information

Accession: GO:0005432
Name: calcium:sodium antiporter activity
Ontology: molecular_function
Synonyms: sodium/calcium exchanger, mitochondrial sodium/calcium ion exchange, sodium:calcium exchange
Alternate IDs: None
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in). Source: PMID:16371597, GOC:curators
Comment: None
History: See term history for GO:0005432 at QuickGO
Chem. react.: has participant sodium(1+)
Subset: None
Related: Link to all genes and gene products annotated to calcium:sodium antiporter activity (excluding "regulates").; Link to all direct and indirect annotations to calcium:sodium antiporter activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for calcium:sodium antiporter activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0003674 molecular_function
GO:0009987 cellular process
GO:0055085 transmembrane transport
GO:0006810 transport
GO:0005215 transporter activity
GO:0022804 active transmembrane transporter activity
GO:0030001 metal ion transport
GO:0034220 monoatomic ion transmembrane transport
GO:0006811 monoatomic ion transport
GO:0022857 transmembrane transporter activity
GO:0006816 calcium ion transport
GO:0098662 inorganic cation transmembrane transport
GO:0098660 inorganic ion transmembrane transport
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0098655 monoatomic cation transmembrane transport
GO:0006812 monoatomic cation transport
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0015291 secondary active transmembrane transporter activity
GO:0022853 active monoatomic ion transmembrane transporter activity
GO:0015297 antiporter activity
GO:0070588 calcium ion transmembrane transport
GO:0022890 inorganic cation transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0006814 sodium ion transport
GO:0015085 calcium ion transmembrane transporter activity
GO:0140828 metal cation:monoatomic cation antiporter activity
GO:0035725 sodium ion transmembrane transport
GO:0015368 calcium:monoatomic cation antiporter activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0005432 calcium:sodium antiporter activity
GO:0008273 calcium, potassium:sodium antiporter activity
GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
GO:1903280 negative regulation of calcium:sodium antiporter activity
GO:1903281 positive regulation of calcium:sodium antiporter activity
GO:1903279 regulation of calcium:sodium antiporter activity

Parents of calcium:sodium antiporter activity (GO:0005432)

subject	relation	object
calcium:sodium antiporter activity	RO:0004009	calcium(2+) (CHEBI:29108)
calcium:sodium antiporter activity	is_a	calcium:monoatomic cation antiporter activity (GO:0015368)
calcium:sodium antiporter activity	RO:0000057	sodium(1+) (CHEBI:29101)
calcium:sodium antiporter activity	is_a	sodium ion transmembrane transporter activity (GO:0015081)

Children of calcium:sodium antiporter activity (GO:0005432)

subject	relation	object
regulation of calcium:sodium antiporter activity (GO:1903279)	RO:0002211	calcium:sodium antiporter activity
negative regulation of calcium:sodium antiporter activity (GO:1903280)	RO:0002212	calcium:sodium antiporter activity
positive regulation of calcium:sodium antiporter activity (GO:1903281)	RO:0002213	calcium:sodium antiporter activity
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential (GO:0086038)	is_a	calcium:sodium antiporter activity
calcium, potassium:sodium antiporter activity (GO:0008273)	is_a	calcium:sodium antiporter activity

Reactome: R-HSA-8949688; R-HSA-425661; R-HSA-8949703
RHEA: 29255