AmiGO 2: Term Details for "membrane attack complex" (GO:0005579)

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Term Information

Accession: GO:0005579
Name: membrane attack complex
Ontology: cellular_component
Synonyms: MAC, TCC, terminal complement complex, membrane attack complex protein alphaM chain, membrane attack complex protein beta2 chain
Alternate IDs: None
Definition: A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. Source: ISBN:0198547684, ISBN:0781735149, GOC:add, ISBN:068340007X
Comment: None
History: See term history for GO:0005579 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to membrane attack complex (excluding "regulates").; Link to all direct and indirect annotations to membrane attack complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for membrane attack complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0005575 cellular_component
GO:0008150 biological_process
GO:0110165 cellular anatomical entity
PR:000050567 protein-containing material entity
GO:0071944 cell periphery
GO:0009987 cellular process
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0001906 cell killing
GO:0098796 membrane protein complex
GO:0005886 plasma membrane
GO:0097278 complement-dependent cytotoxicity
GO:0098797 plasma membrane protein complex
GO:0046930 pore complex
GO:0005579 membrane attack complex

Parents of membrane attack complex (GO:0005579)

subject	relation	object
membrane attack complex	RO:0002216	complement-dependent cytotoxicity (GO:0097278)
membrane attack complex	is_a	plasma membrane protein complex (GO:0098797)
membrane attack complex	is_a	pore complex (GO:0046930)

This term has no children.

Wikipedia: Complement_membrane_attack_complex