AmiGO 2: Term Details for "membrane attack complex" (GO:0005579)

Accession: GO:0005579
Name: membrane attack complex
Ontology: cellular_component
Synonyms: MAC, TCC, terminal complement complex, membrane attack complex protein alphaM chain, membrane attack complex protein beta2 chain
Alternate IDs: None
Definition: A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. Source: ISBN:0198547684, ISBN:0781735149, GOC:add, ISBN:068340007X
Comment: None
History: See term history for GO:0005579 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to membrane attack complex (excluding "regulates").; Link to all direct and indirect annotations to membrane attack complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for membrane attack complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
membrane attack complex	is_a	plasma membrane protein complex (GO:0098797)
membrane attack complex	is_a	pore complex (GO:0046930)
membrane attack complex	RO:0002216	complement-dependent cytotoxicity (GO:0097278)

This term has no children.