AmiGO 2: Term Details for "nuclear lamina" (GO:0005652)

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Term Information

Accession: GO:0005652
Name: nuclear lamina
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane. Source: ISBN:0716731363, ISBN:0198506732
Comment: None
History: See term history for GO:0005652 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to nuclear lamina (excluding "regulates").; Link to all direct and indirect annotations to nuclear lamina (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nuclear lamina (excluding "regulates").

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UBERON:0000061 anatomical structure
CARO:0030000 biological entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0043226 organelle
CARO:0000000 anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
UBERON:0001062 anatomical entity
GO:0043231 intracellular membrane-bounded organelle
CARO:0000006 material anatomical entity
GO:0043233 organelle lumen
CARO:0000003 connected anatomical structure
GO:0070013 intracellular organelle lumen
UBERON:0000465 material anatomical entity
GO:0005634 nucleus
GO:0005575 cellular_component
GO:0031981 nuclear lumen
GO:0034399 nuclear periphery
GO:0005652 nuclear lamina
GO:0005638 lamin filament

Parents of nuclear lamina (GO:0005652)

subject	relation	object
nuclear lamina	BFO:0000050	nuclear periphery (GO:0034399)
nuclear lamina	RO:0002162	Eukaryota (NCBITaxon:2759)
nuclear lamina	is_a	cellular anatomical entity (GO:0110165)

Children of nuclear lamina (GO:0005652)

subject	relation	object
lamin filament (GO:0005638)	BFO:0000050	nuclear lamina

NIF_Subcellular: sao1455996588
Wikipedia: Nuclear_lamina