AmiGO 2: Term Details for "transcription factor TFIIH holo complex" (GO:0005675)

Term Information

Accession: GO:0005675
Name: transcription factor TFIIH holo complex
Ontology: cellular_component
Synonyms: cyclin-dependent protein kinase activating kinase holoenzyme complex, holo TFIIH complex, CAK complex, CDK-activating kinase
Alternate IDs: None
Definition: A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex. Source: GOC:krc, PMID:22308316, PMID:7813015, GOC:ew, PMID:14500720, PMID:22572993
Comment: None
History: See term history for GO:0005675 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to transcription factor TFIIH holo complex (excluding "regulates").; Link to all direct and indirect annotations to transcription factor TFIIH holo complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for transcription factor TFIIH holo complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0009987 cellular process
GO:0008152 metabolic process
GO:0003824 catalytic activity
GO:0044238 primary metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
UBERON:0000061 anatomical structure
CARO:0030000 biological entity
GO:0008150 biological_process
GO:0009058 biosynthetic process
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0016772 transferase activity, transferring phosphorus-containing groups
CARO:0000000 anatomical entity
GO:0065007 biological regulation
GO:0140098 catalytic activity, acting on RNA
CL:0000000 cell
GO:0110165 cellular anatomical structure
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0016779 nucleotidyltransferase activity
GO:0043226 organelle
GO:0032991 protein-containing complex
GO:0009889 regulation of biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0016070 RNA metabolic process
UBERON:0001062 anatomical entity
GO:1902494 catalytic complex
GO:0010467 gene expression
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
CARO:0000006 material anatomical entity
GO:0031974 membrane-enclosed lumen
GO:0043228 membraneless organelle
GO:0003674 molecular_function
GO:0141187 nucleic acid biosynthetic process
GO:0050789 regulation of biological process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0032774 RNA biosynthetic process
GO:0097747 RNA polymerase activity
GO:0016740 transferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0140096 catalytic activity, acting on a protein
GO:0007049 cell cycle
CARO:0000003 connected anatomical structure
GO:0006351 DNA-templated transcription
GO:0043232 intracellular membraneless organelle
GO:0140535 intracellular protein-containing complex
GO:0016301 kinase activity
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0043233 organelle lumen
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:1990234 transferase complex
GO:0061695 transferase complex, transferring phosphorus-containing groups
GO:0005575 cellular_component
GO:0005694 chromosome
GO:0003899 DNA-directed RNA polymerase activity
GO:0043231 intracellular membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0005634 nucleus
GO:0004672 protein kinase activity
GO:0051726 regulation of cell cycle
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030880 RNA polymerase complex
GO:0006366 transcription by RNA polymerase II
GO:0140110 transcription regulator activity
GO:0000785 chromatin
GO:0097472 cyclin-dependent protein kinase activity
GO:0003700 DNA-binding transcription factor activity
GO:0000428 DNA-directed RNA polymerase complex
GO:0031981 nuclear lumen
GO:0140513 nuclear protein-containing complex
GO:1902911 protein kinase complex
GO:0004674 protein serine/threonine kinase activity
GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity
GO:1902554 serine/threonine protein kinase complex
GO:0000307 cyclin-dependent protein kinase holoenzyme complex
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0055029 nuclear DNA-directed RNA polymerase complex
GO:0005654 nucleoplasm
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0005667 transcription regulator complex
GO:0032806 carboxy-terminal domain protein kinase complex
GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex
GO:0090575 RNA polymerase II transcription regulator complex
GO:0016591 RNA polymerase II, holoenzyme
GO:0005675 transcription factor TFIIH holo complex
GO:0000438 core TFIIH complex portion of holo TFIIH complex
GO:0070985 transcription factor TFIIK complex

Parents of transcription factor TFIIH holo complex (GO:0005675)

subject	relation	object
transcription factor TFIIH holo complex	RO:0002162	Eukaryota (NCBITaxon:2759)
transcription factor TFIIH holo complex	is_a	RNA polymerase II transcription regulator complex (GO:0090575)
transcription factor TFIIH holo complex	BFO:0000050	RNA polymerase II, holoenzyme (GO:0016591)
transcription factor TFIIH holo complex	is_a	carboxy-terminal domain protein kinase complex (GO:0032806)
transcription factor TFIIH holo complex	BFO:0000051	transcription factor TFIIH core complex (GO:0000439)
transcription factor TFIIH holo complex	is_a	nuclear cyclin-dependent protein kinase holoenzyme complex (GO:0019908)

Children of transcription factor TFIIH holo complex (GO:0005675)

subject	relation	object
transcription factor TFIIH holo complex binding (GO:0062058)	RO:0004009	transcription factor TFIIH holo complex
core TFIIH complex portion of holo TFIIH complex (GO:0000438)	BFO:0000050	transcription factor TFIIH holo complex
transcription factor TFIIK complex (GO:0070985)	BFO:0000050	transcription factor TFIIH holo complex

GONUTS Add usage comments for this term on the GONUTS wiki.