AmiGO 2: Term Details for "mitochondrial permeability transition pore complex" (GO:0005757)

Accession: GO:0005757
Name: mitochondrial permeability transition pore complex
Ontology: cellular_component
Synonyms: MPTP complex, mitochondrial PT pore complex, PTPC
Alternate IDs: None
Definition: A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). Source: PMID:10393078
Comment: None
History: See term history for GO:0005757 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to mitochondrial permeability transition pore complex (excluding "regulates").; Link to all direct and indirect annotations to mitochondrial permeability transition pore complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for mitochondrial permeability transition pore complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
mitochondrial permeability transition pore complex	is_a	mitochondrial protein-containing complex (GO:0098798)
mitochondrial permeability transition pore complex	is_a	pore complex (GO:0046930)
mitochondrial permeability transition pore complex	BFO:0000050	mitochondrial envelope (GO:0005740)
mitochondrial permeability transition pore complex	RO:0002162	Eukaryota (NCBITaxon:2759)

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