AmiGO 2: Term Details for "heterotrimeric G-protein complex" (GO:0005834)

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Term Information

Accession: GO:0005834
Name: heterotrimeric G-protein complex
Ontology: cellular_component
Synonyms: heterotrimeric G-protein GTPase activity, heterotrimeric G-protein GTPase, alpha-subunit, heterotrimeric G-protein GTPase, beta-subunit, heterotrimeric G-protein GTPase, gamma-subunit
Alternate IDs: None
Definition: Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. Source: ISBN:0198547684
Comment: See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'.
History: See term history for GO:0005834 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to heterotrimeric G-protein complex (excluding "regulates").; Link to all direct and indirect annotations to heterotrimeric G-protein complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for heterotrimeric G-protein complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
GO:0003824 catalytic activity
UBERON:0001062 anatomical entity
GO:0016787 hydrolase activity
CARO:0000006 material anatomical entity
CARO:0000003 connected anatomical structure
GO:0016817 hydrolase activity, acting on acid anhydrides
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0110165 cellular anatomical entity
GO:0005575 cellular_component
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016020 membrane
GO:0003674 molecular_function
PR:000050567 protein-containing material entity
GO:0016462 pyrophosphatase activity
GO:0098552 side of membrane
GO:0071944 cell periphery
GO:0098562 cytoplasmic side of membrane
GO:0019898 extrinsic component of membrane
GO:0005886 plasma membrane
GO:0032991 protein-containing complex
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:1902494 catalytic complex
GO:0009898 cytoplasmic side of plasma membrane
GO:0019897 extrinsic component of plasma membrane
GO:0003924 GTPase activity
GO:0098796 membrane protein complex
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:1905360 GTPase complex
GO:0098797 plasma membrane protein complex
GO:0005834 heterotrimeric G-protein complex

Parents of heterotrimeric G-protein complex (GO:0005834)

subject	relation	object
heterotrimeric G-protein complex	is_a	plasma membrane protein complex (GO:0098797)
heterotrimeric G-protein complex	BFO:0000050	extrinsic component of cytoplasmic side of plasma membrane (GO:0031234)
heterotrimeric G-protein complex	is_a	GTPase complex (GO:1905360)

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