AmiGO 2: Term Details for "nuclear cap binding complex" (GO:0005846)

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Term Information

Accession: GO:0005846
Name: nuclear cap binding complex
Ontology: cellular_component
Synonyms: nuclear CBC, CBC, NCBP-NIP1 complex, mRNA cap binding complex, snRNA cap binding complex
Alternate IDs: None
Definition: A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export. Source: PMID:16043498
Comment: Note that this complex can be found in the cytoplasm as well as the nucleus.
History: See term history for GO:0005846 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to nuclear cap binding complex (excluding "regulates").; Link to all direct and indirect annotations to nuclear cap binding complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nuclear cap binding complex (excluding "regulates").

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GO:0003674 molecular_function
GO:0005488 binding
GO:0097159 organic cyclic compound binding
GO:0005575 cellular_component
GO:0003676 nucleic acid binding
PR:000050567 protein-containing material entity
GO:0032991 protein-containing complex
GO:0003723 RNA binding
GO:0140535 intracellular protein-containing complex
GO:0000339 RNA cap binding
GO:0034518 RNA cap binding complex
GO:0005846 nuclear cap binding complex

Parents of nuclear cap binding complex (GO:0005846)

subject	relation	object
nuclear cap binding complex	is_a	RNA cap binding complex (GO:0034518)

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