AmiGO 2: Term Details for "actin filament" (GO:0005884)

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Term Information

Accession: GO:0005884
Name: actin filament
Ontology: cellular_component
Synonyms: microfilament
Alternate IDs: None
Definition: A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. Source: ISBN:0198506732, GOC:mah, PMID:10666339
Comment: None
History: See term history for GO:0005884 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to actin filament (excluding "regulates").; Link to all direct and indirect annotations to actin filament (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for actin filament (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
UBERON:0000061 anatomical structure
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
CL:0000000 cell
GO:0110165 cellular anatomical structure
GO:0005575 cellular_component
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0043229 intracellular organelle
GO:0043228 membraneless organelle
GO:0099080 supramolecular complex
GO:0043232 intracellular membraneless organelle
GO:0099081 supramolecular polymer
GO:0005856 cytoskeleton
GO:0099512 supramolecular fiber
GO:0015629 actin cytoskeleton
GO:0099513 polymeric cytoskeletal fiber
GO:0005884 actin filament
GO:0061834 actin filament branch point
GO:1903145 actin filament of cell cortex of cell tip
GO:1903144 actomyosin contractile ring actin filament
GO:0031941 filamentous actin

Parents of actin filament (GO:0005884)

subject	relation	object
actin filament	RO:0002162	cellular organisms (NCBITaxon:131567)
actin filament	BFO:0000050	actin cytoskeleton (GO:0015629)
actin filament	is_a	polymeric cytoskeletal fiber (GO:0099513)

Children of actin filament (GO:0005884)

subject	relation	object
actin-based cell projection (GO:0098858)	BFO:0000051	actin filament
actin filament branch point (GO:0061834)	BFO:0000050	actin filament
actin filament-based transport (GO:0099515)	RO:0002341	actin filament
actin filament organization (GO:0007015)	RO:0002592	actin filament
filamentous actin (GO:0031941)	BFO:0000050	actin filament
actin filament bundle (GO:0032432)	BFO:0000051	actin filament
actin wave (GO:0062201)	BFO:0000051	actin filament
actin filament of cell cortex of cell tip (GO:1903145)	is_a	actin filament
microfilament motor activity (GO:0000146)	RO:0000057	actin filament
actin filament uncapping (GO:0051695)	RO:0000057	actin filament
mating projection actin fusion focus (GO:1990819)	BFO:0000051	actin filament
actomyosin contractile ring actin filament (GO:1903144)	is_a	actin filament
actin filament-based process (GO:0030029)	RO:0002608	actin filament

FMA: 63850
NIF_Subcellular: sao1588493326
Wikipedia: Actin