AmiGO 2: Term Details for "phosphatidylinositol 3-kinase complex" (GO:0005942)

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Term Information

Accession: GO:0005942
Name: phosphatidylinositol 3-kinase complex
Ontology: cellular_component
Synonyms: 1-phosphatidylinositol 3-kinase complex, PI3K complex, phosphoinositide 3-kinase complex, PI3-kinase p85-subunit alpha- PI3-kinase p110 complex, PIK3C3-PIK3R4 complex, PIK3CA-PIK3R1 complex
Alternate IDs: None
Definition: A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too. Source: GOC:bf, PMID:24587488
Comment: For discussion of membrane association, please see https://sourceforge.net/p/geneontology/ontology-requests/11559/
History: See term history for GO:0005942 at QuickGO
Chem. react.: None
Subset: goslim_pir
Related: Link to all genes and gene products annotated to phosphatidylinositol 3-kinase complex (excluding "regulates").; Link to all direct and indirect annotations to phosphatidylinositol 3-kinase complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for phosphatidylinositol 3-kinase complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0009987 cellular process
GO:0006629 lipid metabolic process
GO:0071704 organic substance metabolic process
GO:0006793 phosphorus metabolic process
GO:0044238 primary metabolic process
GO:0044255 cellular lipid metabolic process
GO:1901576 organic substance biosynthetic process
GO:0019637 organophosphate metabolic process
GO:0006796 phosphate-containing compound metabolic process
CARO:0030000 biological entity
GO:0044249 cellular biosynthetic process
GO:0046486 glycerolipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0090407 organophosphate biosynthetic process
GO:0006644 phospholipid metabolic process
CARO:0000000 anatomical entity
GO:0045017 glycerolipid biosynthetic process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
UBERON:0001062 anatomical entity
GO:0046474 glycerophospholipid biosynthetic process
CARO:0000006 material anatomical entity
GO:0003674 molecular_function
GO:0046488 phosphatidylinositol metabolic process
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0003824 catalytic activity
CARO:0000003 connected anatomical structure
GO:0016301 kinase activity
UBERON:0000465 material anatomical entity
GO:0006661 phosphatidylinositol biosynthetic process
GO:0032991 protein-containing complex
UBERON:0000061 anatomical structure
GO:1902494 catalytic complex
GO:0110165 cellular anatomical entity
GO:0005575 cellular_component
GO:0001727 lipid kinase activity
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0016773 phosphotransferase activity, alcohol group as acceptor
PR:000050567 protein-containing material entity
GO:0016740 transferase activity
GO:0016020 membrane
GO:0052742 phosphatidylinositol kinase activity
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
GO:1990234 transferase complex
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019898 extrinsic component of membrane
GO:0098796 membrane protein complex
GO:0061695 transferase complex, transferring phosphorus-containing groups
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0097651 phosphatidylinositol 3-kinase complex, class I
GO:0097652 phosphatidylinositol 3-kinase complex, class II
GO:0035032 phosphatidylinositol 3-kinase complex, class III

Parents of phosphatidylinositol 3-kinase complex (GO:0005942)

subject	relation	object
phosphatidylinositol 3-kinase complex	is_a	membrane protein complex (GO:0098796)
phosphatidylinositol 3-kinase complex	BFO:0000050	extrinsic component of membrane (GO:0019898)
phosphatidylinositol 3-kinase complex	RO:0002215	1-phosphatidylinositol-3-kinase activity (GO:0016303)
phosphatidylinositol 3-kinase complex	is_a	transferase complex, transferring phosphorus-containing groups (GO:0061695)

Children of phosphatidylinositol 3-kinase complex (GO:0005942)

subject	relation	object
phosphatidylinositol 3-kinase complex, class II (GO:0097652)	is_a	phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class I (GO:0097651)	is_a	phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class III (GO:0035032)	is_a	phosphatidylinositol 3-kinase complex

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