OBSOLETE. A mitochondrial complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.
Source:ISBN:0471331309,
GOC:mtg_sensu,
ISBN:0716720094
Link
to all genes and gene products annotated to obsolete mitochondrial pyruvate dehydrogenase complex (excluding "regulates").
Link
to all direct and indirect annotations
to obsolete mitochondrial pyruvate dehydrogenase complex (excluding "regulates").
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to all direct and indirect annotations download (limited to first 10,000)
for obsolete mitochondrial pyruvate dehydrogenase complex (excluding "regulates").