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Accession
GO:0006127
Name
glycerophosphate shuttle
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle. Source: GOC:mtg_electron_transport, GOC:jl, PMID:16368075, ISBN:0716720094
Comment
None
History
See term history for GO:0006127 at QuickGO
Chem. react.
has participant glycerone phosphate(2-)
has participant sn-glycerol 3-phosphate(2-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of glycerophosphate shuttle (GO:0006127)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glycerophosphate shuttle [RO:0002162 relation] RO:0002162  Eukaryota (NCBITaxon:2759)
glycerophosphate shuttle [RO:0004009 relation] RO:0004009  1,4-benzoquinones (CHEBI:132124)
glycerophosphate shuttle [BFO:0000051 relation] BFO:0000051  glycerol-3-phosphate dehydrogenase (NAD+) activity (GO:0141152)
glycerophosphate shuttle [is_a relation] is_a  phenol-containing compound metabolic process (GO:0018958)
glycerophosphate shuttle [is_a relation] is_a  NADH oxidation (GO:0006116)
glycerophosphate shuttle [RO:0000057 relation] RO:0000057  glycerone phosphate(2-) (CHEBI:57642)
glycerophosphate shuttle [RO:0000057 relation] RO:0000057  sn-glycerol 3-phosphate(2-) (CHEBI:57597)
glycerophosphate shuttle [BFO:0000050 relation] BFO:0000050  respiratory electron transport chain (GO:0022904)
glycerophosphate shuttle [RO:0004008 relation] RO:0004008  NAD(1-) (CHEBI:57540)
glycerophosphate shuttle [BFO:0000051 relation] BFO:0000051  glycerol-3-phosphate dehydrogenase (quinone) activity (GO:0004368)
glycerophosphate shuttle [RO:0004008 relation] RO:0004008  hydroquinones (CHEBI:24646)
glycerophosphate shuttle [is_a relation] is_a  quinone metabolic process (GO:1901661)
glycerophosphate shuttle [RO:0004009 relation] RO:0004009  NADH(2-) (CHEBI:57945)

This term has no children.

MetaCyc
PWY-6118