Term Information

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Accession
GO:0006265
Name
DNA topological change
Ontology
biological_process
Synonyms
DNA underwinding
Alternate IDs
None
Definition
The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number. Source: ISBN:0935702490, ISBN:071673706X
Comment
Note that the synonym 'DNA underwinding' should not be confused with 'DNA unwinding ; GO:0006268', which refers to DNA strand separation, and is a type of geometric change. GO:0006265 refers to alteration of the superhelical density of double-stranded DNA. Note that DNA topological change and DNA geometric change (GO:0032392) are distinct, but are usually coupled in vivo.
History
See term history for GO:0006265 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of DNA topological change (GO:0006265)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA topological change [is_a relation] is_a  DNA metabolic process (GO:0006259)
DNA topological change [is_a relation] is_a  DNA conformation change (GO:0071103)
Children of DNA topological change (GO:0006265)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA topoisomerase III-beta-TDRD3 complex (GO:0140225) [RO:0002216 relation] RO:0002216  DNA topological change
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