AmiGO 2: Term Details for "base-excision repair, AP site formation" (GO:0006285)

Accession: GO:0006285
Name: base-excision repair, AP site formation
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired. Source: ISBN:0815316194
Comment: None
History: See term history for GO:0006285 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to base-excision repair, AP site formation (excluding "regulates").; Link to all direct and indirect annotations to base-excision repair, AP site formation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for base-excision repair, AP site formation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
base-excision repair, AP site formation	BFO:0000050	base-excision repair (GO:0006284)
base-excision repair, AP site formation	is_a	DNA metabolic process (GO:0006259)

subject	relation	object
base-excision repair, AP site formation via deaminated base removal (GO:0097510)	is_a	base-excision repair, AP site formation
depyrimidination (GO:0045008)	is_a	base-excision repair, AP site formation
depurination (GO:0045007)	is_a	base-excision repair, AP site formation

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