Term Information

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Accession
GO:0006303
Name
double-strand break repair via nonhomologous end joining
Ontology
biological_process
Synonyms
NHEJ
Alternate IDs
None
Definition
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. Source: GOC:rph, PMID:24837021, PMID:10827453
Comment
None
History
See term history for GO:0006303 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of double-strand break repair via nonhomologous end joining (GO:0006303)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
double-strand break repair via nonhomologous end joining [is_a relation] is_a  double-strand break repair (GO:0006302)
Children of double-strand break repair via nonhomologous end joining (GO:0006303)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
double-strand break repair via classical nonhomologous end joining (GO:0097680) [is_a relation] is_a  double-strand break repair via nonhomologous end joining
nonhomologous end joining complex (GO:0070419) [RO:0002216 relation] RO:0002216  double-strand break repair via nonhomologous end joining
positive regulation of double-strand break repair via nonhomologous end joining (GO:2001034) [RO:0002213 relation] RO:0002213  double-strand break repair via nonhomologous end joining
gap filling involved in double-strand break repair via nonhomologous end joining (GO:0061674) [BFO:0000050 relation] BFO:0000050  double-strand break repair via nonhomologous end joining
regulation of double-strand break repair via nonhomologous end joining (GO:2001032) [RO:0002211 relation] RO:0002211  double-strand break repair via nonhomologous end joining
double-strand break repair via alternative nonhomologous end joining (GO:0097681) [is_a relation] is_a  double-strand break repair via nonhomologous end joining
negative regulation of double-strand break repair via nonhomologous end joining (GO:2001033) [RO:0002212 relation] RO:0002212  double-strand break repair via nonhomologous end joining
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