AmiGO 2: Term Details for "7-methylguanosine mRNA capping" (GO:0006370)

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Term Information

Accession: GO:0006370
Name: 7-methylguanosine mRNA capping
Ontology: biological_process
Synonyms: 5' mRNA capping, 5'-end mRNA processing, mRNA capping, 5' end capping, 5'-end processing
Alternate IDs: None
Definition: The sequence of enzymatic reactions by which the mRNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively. Source: GOC:mah, PMID:9266685
Comment: None
History: See term history for GO:0006370 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to 7-methylguanosine mRNA capping (excluding "regulates").; Link to all direct and indirect annotations to 7-methylguanosine mRNA capping (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 7-methylguanosine mRNA capping (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0006396 RNA processing
GO:0010467 gene expression
GO:0006139 nucleobase-containing compound metabolic process
GO:0000966 RNA 5'-end processing
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0036260 RNA capping
GO:0009452 7-methylguanosine RNA capping
GO:0006397 mRNA processing
GO:0141187 nucleic acid biosynthetic process
GO:0006370 7-methylguanosine mRNA capping
GO:0004482 mRNA 5'-cap (guanine-N7-)-methyltransferase activity

Parents of 7-methylguanosine mRNA capping (GO:0006370)

subject	relation	object
7-methylguanosine mRNA capping	is_a	mRNA processing (GO:0006397)
7-methylguanosine mRNA capping	RO:0004008	capped_mRNA (SO:0000862)
7-methylguanosine mRNA capping	is_a	7-methylguanosine RNA capping (GO:0009452)
7-methylguanosine mRNA capping	is_a	nucleic acid biosynthetic process (GO:0141187)

Children of 7-methylguanosine mRNA capping (GO:0006370)

subject	relation	object
mRNA 5'-cap (guanine-N7-)-methyltransferase activity (GO:0004482)	BFO:0000050	7-methylguanosine mRNA capping

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