Term Information

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Accession
GO:0006388
Name
tRNA splicing, via endonucleolytic cleavage and ligation
Ontology
biological_process
Synonyms
tRNA-Y splicing
Alternate IDs
None
Definition
Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. Source: GOC:krc, PMID:9582290, ISBN:0879695897
Comment
Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
History
See term history for GO:0006388 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0006388 from QuickGO

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Parents of tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tRNA splicing, via endonucleolytic cleavage and ligation [is_a relation] is_a  tRNA processing (GO:0008033)
tRNA splicing, via endonucleolytic cleavage and ligation [is_a relation] is_a  RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)
Children of tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tRNA exon ligation (GO:0000968) [BFO:0000050 relation] BFO:0000050  tRNA splicing, via endonucleolytic cleavage and ligation
tRNA-type intron splice site recognition and cleavage (GO:0000379) [BFO:0000050 relation] BFO:0000050  tRNA splicing, via endonucleolytic cleavage and ligation
None.