Term Information

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Accession
GO:0006616
Name
SRP-dependent cotranslational protein targeting to membrane, translocation
Ontology
biological_process
Synonyms
SRP-dependent cotranslational membrane targeting, translocation, SRP-dependent cotranslational protein-membrane targeting, translocation, translocation during SRP-dependent cotranslational protein targeting to membrane, ER translocation
Alternate IDs
None
Definition
The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. Source: ISBN:0716731363
Comment
None
History
See term history for GO:0006616 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of SRP-dependent cotranslational protein targeting to membrane, translocation (GO:0006616)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
SRP-dependent cotranslational protein targeting to membrane, translocation [BFO:0000050 relation] BFO:0000050  SRP-dependent cotranslational protein targeting to membrane (GO:0006614)
SRP-dependent cotranslational protein targeting to membrane, translocation [is_a relation] is_a  intracellular protein transmembrane transport (GO:0065002)

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