AmiGO 2: Term Details for "DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" (GO:0006978)

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Term Information

Accession: GO:0006978
Name: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage. Source: PMID:10967424
Comment: None
History: See term history for GO:0006978 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (excluding "regulates").; Link to all direct and indirect annotations to DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
CL:0000000 cell
GO:0007154 cell communication
GO:0110165 cellular anatomical entity
GO:0051716 cellular response to stimulus
GO:0050794 regulation of cellular process
GO:0006950 response to stress
GO:0023052 signaling
GO:0033554 cellular response to stress
GO:0005622 intracellular anatomical structure
GO:0007165 signal transduction
GO:0006974 DNA damage response
GO:0035556 intracellular signal transduction
GO:0072331 signal transduction by p53 class mediator
GO:0042770 signal transduction in response to DNA damage
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0042772 DNA damage response, signal transduction resulting in transcription
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

Parents of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:0006978)

subject	relation	object
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	is_a	DNA damage response, signal transduction by p53 class mediator (GO:0030330)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	is_a	DNA damage response, signal transduction resulting in transcription (GO:0042772)

Children of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:0006978)

subject	relation	object
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:1902162)	RO:0002211	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:1902163)	RO:0002212	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:1902164)	RO:0002213	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator