AmiGO 2: Term Details for "ER overload response" (GO:0006983)

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Term Information

Accession: GO:0006983
Name: ER overload response
Ontology: biological_process
Synonyms: EOR, ER-overload response, endoplasmic reticulum overload response, EOR-mediated NF-kappaB activation, EOR-mediated activation of NF-kappaB, positive regulation of NF-kappaB transcription factor activity by EOR, positive regulation of NF-kappaB transcription factor activity by ER overload response
Alternate IDs: GO:0006985
Definition: The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB. Source: PMID:10390516
Comment: None
History: See term history for GO:0006983 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to ER overload response (excluding "regulates").; Link to all direct and indirect annotations to ER overload response (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ER overload response (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0050794 regulation of cellular process
GO:0006950 response to stress
GO:0023052 signaling
GO:0033554 cellular response to stress
GO:0009607 response to biotic stimulus
GO:0007165 signal transduction
GO:0071216 cellular response to biotic stimulus
GO:0006984 ER-nucleus signaling pathway
GO:0034976 response to endoplasmic reticulum stress
GO:0006983 ER overload response
GO:0002234 detection of endoplasmic reticulum overloading
GO:0034263 positive regulation of autophagy in response to ER overload

Parents of ER overload response (GO:0006983)

subject	relation	object
ER overload response	is_a	response to endoplasmic reticulum stress (GO:0034976)
ER overload response	is_a	cellular response to biotic stimulus (GO:0071216)
ER overload response	is_a	ER-nucleus signaling pathway (GO:0006984)

Children of ER overload response (GO:0006983)

subject	relation	object
detection of endoplasmic reticulum overloading (GO:0002234)	is_a	ER overload response
positive regulation of autophagy in response to ER overload (GO:0034263)	is_a	ER overload response

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