Term Information

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Accession
GO:0007224
Name
smoothened signaling pathway
Ontology
biological_process
Synonyms
hedgehog signaling pathway, smoothened signalling pathway, Shh signaling pathway, Sonic hedgehog signaling pathway, hh signaling pathway, hh signalling pathway
Alternate IDs
None
Definition
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. Source: PMID:15057936, PMID:15205520, GOC:mah
Comment
None
History
See term history for GO:0007224 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0007224 from QuickGO

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Parents of smoothened signaling pathway (GO:0007224)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
smoothened signaling pathway [is_a relation] is_a  cell surface receptor signaling pathway (GO:0007166)
Children of smoothened signaling pathway (GO:0007224)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ciliary receptor clustering involved in smoothened signaling pathway (GO:0060830) [BFO:0000050 relation] BFO:0000050  smoothened signaling pathway
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation (GO:0021938) [is_a relation] is_a  smoothened signaling pathway
smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021910) [is_a relation] is_a  smoothened signaling pathway
smoothened signaling pathway involved in lung development (GO:0060506) [is_a relation] is_a  smoothened signaling pathway
negative regulation of smoothened signaling pathway (GO:0045879) [RO:0002212 relation] RO:0002212  smoothened signaling pathway
smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:0060831) [is_a relation] is_a  smoothened signaling pathway
regulation of smoothened signaling pathway (GO:0008589) [RO:0002211 relation] RO:0002211  smoothened signaling pathway
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation (GO:0003271) [is_a relation] is_a  smoothened signaling pathway
mesenchymal smoothened signaling pathway involved in prostate gland development (GO:0060783) [is_a relation] is_a  smoothened signaling pathway
smoothened signaling pathway involved in growth plate cartilage chondrocyte development (GO:0003435) [is_a relation] is_a  smoothened signaling pathway
positive regulation of smoothened signaling pathway (GO:0045880) [RO:0002213 relation] RO:0002213  smoothened signaling pathway