AmiGO 2: Term Details for "chemokine activity" (GO:0008009)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0008009
Name: chemokine activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. Source: PMID:12183377, GOC:BHF, Wikipedia:Chemokine, GOC:rl
Comment: None
History: See term history for GO:0008009 at QuickGO
Chem. react.: None
Subset: goslim_chembl
Related: Link to all genes and gene products annotated to chemokine activity (excluding "regulates").; Link to all direct and indirect annotations to chemokine activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for chemokine activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0008150 biological_process
GO:0065007 biological regulation
GO:0003674 molecular_function
GO:0005488 binding
GO:0009987 cellular process
GO:0098772 molecular function regulator activity
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0040011 locomotion
GO:0140677 molecular function activator activity
GO:0060089 molecular transducer activity
GO:0005515 protein binding
GO:0050794 regulation of cellular process
GO:0009605 response to external stimulus
GO:0023052 signaling
GO:0030545 signaling receptor regulator activity
GO:0048870 cell motility
GO:0042221 response to chemical
GO:0007165 signal transduction
GO:0030546 signaling receptor activator activity
GO:0038023 signaling receptor activity
GO:0005102 signaling receptor binding
GO:0042330 taxis
GO:0016477 cell migration
GO:0070887 cellular response to chemical stimulus
GO:0006935 chemotaxis
GO:0005126 cytokine receptor binding
GO:0001664 G protein-coupled receptor binding
GO:0048018 receptor ligand activity
GO:0060326 cell chemotaxis
GO:0042379 chemokine receptor binding
GO:0005125 cytokine activity
GO:0008009 chemokine activity
GO:1900137 negative regulation of chemokine activity
GO:1900136 regulation of chemokine activity

Parents of chemokine activity (GO:0008009)

subject	relation	object
chemokine activity	BFO:0000050	cell chemotaxis (GO:0060326)
chemokine activity	is_a	chemokine receptor binding (GO:0042379)
chemokine activity	is_a	cytokine activity (GO:0005125)

Children of chemokine activity (GO:0008009)

subject	relation	object
negative regulation of chemokine activity (GO:1900137)	RO:0002212	chemokine activity
regulation of chemokine activity (GO:1900136)	RO:0002211	chemokine activity

GONUTS Add usage comments for this term on the GONUTS wiki.