Term Information

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Accession
GO:0008116
Name
prostaglandin-I synthase activity
Ontology
molecular_function
Synonyms
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity, PGI(2) synthase activity, PGI(2) synthetase activity, PGI2 synthase activity, PGI2 synthetase activity, prostacyclin synthase activity, prostacycline synthetase activity, prostagladin I2 synthetase activity, cytochrome P450 CYP8A1
Alternate IDs
None
Definition
Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2). Source: RHEA:23580, EC:5.3.99.4
Comment
None
History
See term history for GO:0008116 at QuickGO
Chem. react.
has participant prostaglandin H2(1-)
has participant prostaglandin I2(1-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of prostaglandin-I synthase activity (GO:0008116)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
prostaglandin-I synthase activity [is_a relation] is_a  intramolecular oxidoreductase activity (GO:0016860)
prostaglandin-I synthase activity [RO:0000057 relation] RO:0000057  prostaglandin H2(1-) (CHEBI:57405)
prostaglandin-I synthase activity [RO:0000057 relation] RO:0000057  prostaglandin I2(1-) (CHEBI:57403)

This term has no children.

EC
5.3.99.4
KEGG_REACTION
R02267
MetaCyc
PROSTAGLANDIN-I-SYNTHASE-RXN
Reactome
R-HSA-76496
RHEA
23580