AmiGO 2: Term Details for "thiopurine S-methyltransferase activity" (GO:0008119)

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Term Information

Accession: GO:0008119
Name: thiopurine S-methyltransferase activity
Ontology: molecular_function
Synonyms: 6-thiopurine transmethylase activity, S-adenosyl-L-methionine:thiopurine S-methyltransferase activity, TPMT, mercaptopurine methyltransferase activity, thiopurine methyltransferase activity
Alternate IDs: None
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. Source: EC:2.1.1.67
Comment: None
History: See term history for GO:0008119 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to thiopurine S-methyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations to thiopurine S-methyltransferase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for thiopurine S-methyltransferase activity (excluding "regulates").

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016741 transferase activity, transferring one-carbon groups
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0008172 S-methyltransferase activity
GO:0008119 thiopurine S-methyltransferase activity

Parents of thiopurine S-methyltransferase activity (GO:0008119)

subject	relation	object
thiopurine S-methyltransferase activity	is_a	S-methyltransferase activity (GO:0008172)
thiopurine S-methyltransferase activity	is_a	S-adenosylmethionine-dependent methyltransferase activity (GO:0008757)

This term has no children.

EC: 2.1.1.67
MetaCyc: THIOPURINE-S-METHYLTRANSFERASE-RXN
Reactome: R-HSA-5603379; R-HSA-158609; R-HSA-9748983; R-HSA-9748979