AmiGO 2: Term Details for "4-alpha-hydroxytetrahydrobiopterin dehydratase activity" (GO:0008124)

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Term Information

Accession: GO:0008124
Name: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
Ontology: molecular_function
Synonyms: 4a-hydroxytetrahydrobiopterin dehydratase activity, pterin-4-alpha-carbinolamine dehydratase activity, pterin-4a-carbinolamine dehydratase activity, (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming], 4-alpha-hydroxy-tetrahydropterin dehydratase activity, 4a-hydroxytetrahydrobiopterin hydro-lyase activity, 4alpha-hydroxy-tetrahydropterin dehydratase activity, pterin-4alpha-carbinolamine dehydratase activity, tetrahydrobiopterin dehydratase activity
Alternate IDs: None
Definition: Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. Source: EC:4.2.1.96, RHEA:11920
Comment: None
History: See term history for GO:0008124 at QuickGO
Chem. react.: has participant 4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin; has participant (6R)-L-erythro-6,7-dihydrobiopterin; has participant water
Subset: None
Related: Link to all genes and gene products annotated to 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (excluding "regulates").; Link to all direct and indirect annotations to 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (excluding "regulates").

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016835 carbon-oxygen lyase activity
GO:0016836 hydro-lyase activity
GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity

Parents of 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (GO:0008124)

subject	relation	object
4-alpha-hydroxytetrahydrobiopterin dehydratase activity	is_a	hydro-lyase activity (GO:0016836)
4-alpha-hydroxytetrahydrobiopterin dehydratase activity	RO:0000057	4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin (CHEBI:15642)
4-alpha-hydroxytetrahydrobiopterin dehydratase activity	RO:0000057	(6R)-L-erythro-6,7-dihydrobiopterin (CHEBI:43120)
4-alpha-hydroxytetrahydrobiopterin dehydratase activity	RO:0000057	water (CHEBI:15377)

This term has no children.

EC: 4.2.1.96
KEGG_REACTION: R04734
MetaCyc: RXN-7908
Reactome: R-HSA-71146
RHEA: 11920