AmiGO 2: Term Details for "NADH dehydrogenase (ubiquinone) activity" (GO:0008137)

Term Information

Accession: GO:0008137
Name: NADH dehydrogenase (ubiquinone) activity
Ontology: molecular_function
Synonyms: ubiquinone reductase activity, DPNH-coenzyme Q reductase activity, DPNH-ubiquinone reductase activity, NADH coenzyme Q1 reductase activity, NADH-CoQ oxidoreductase activity, NADH-CoQ reductase activity, NADH-Q6 oxidoreductase activity, NADH-coenzyme Q oxidoreductase activity, NADH-coenzyme Q reductase activity, NADH-ubiquinone oxidoreductase activity, NADH-ubiquinone reductase activity, NADH-ubiquinone-1 reductase activity, NADH:ubiquinone oxidoreductase activity, NADH:ubiquinone oxidoreductase complex activity, coenzyme Q reductase activity, complex 1 dehydrogenase activity, complex I (NADH:Q1 oxidoreductase) activity, complex I (electron transport chain) activity, complex I (mitochondrial electron transport) activity, dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity, electron transfer complex I activity, reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity, type 1 dehydrogenase activity, mitochondrial electron transport complex 1 activity, mitochondrial electron transport complex I activity
Alternate IDs: None
Definition: Catalysis of the reaction: NADH + ubiquinone + 5 H+(in) = NAD+ + ubiquinol + 4 H+(out). Source: RHEA:29091
Comment: None
History: See term history for GO:0008137 at QuickGO
Chem. react.: has participant NAD(1-); has participant ubiquinones; has participant NADH(2-); has participant ubiquinol; has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to NADH dehydrogenase (ubiquinone) activity (excluding "regulates").; Link to all direct and indirect annotations to NADH dehydrogenase (ubiquinone) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for NADH dehydrogenase (ubiquinone) activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0009987 cellular process
GO:0003674 molecular_function
GO:0006810 transport
GO:0055085 transmembrane transport
GO:0005215 transporter activity
GO:0022857 transmembrane transporter activity
GO:0022804 active transmembrane transporter activity
GO:0015399 primary active transmembrane transporter activity
GO:0009055 electron transfer activity
GO:0015453 oxidoreduction-driven active transmembrane transporter activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0045271 respiratory chain complex I

Parents of NADH dehydrogenase (ubiquinone) activity (GO:0008137)

subject	relation	object
NADH dehydrogenase (ubiquinone) activity	RO:0000057	NAD(1-) (CHEBI:57540)
NADH dehydrogenase (ubiquinone) activity	RO:0000057	ubiquinones (CHEBI:16389)
NADH dehydrogenase (ubiquinone) activity	is_a	oxidoreduction-driven active transmembrane transporter activity (GO:0015453)
NADH dehydrogenase (ubiquinone) activity	is_a	electron transfer activity (GO:0009055)
NADH dehydrogenase (ubiquinone) activity	RO:0000057	NADH(2-) (CHEBI:57945)
NADH dehydrogenase (ubiquinone) activity	RO:0000057	ubiquinol (CHEBI:17976)
NADH dehydrogenase (ubiquinone) activity	RO:0000057	hydron (CHEBI:15378)

Children of NADH dehydrogenase (ubiquinone) activity (GO:0008137)

subject	relation	object
respiratory chain complex I (GO:0045271)	RO:0002215	NADH dehydrogenase (ubiquinone) activity

EC: 7.1.1.2
MetaCyc: NADH-DEHYDROG-A-RXN
Reactome: R-HSA-163217
RHEA: 29091