AmiGO 2: Term Details for "phosphatidate phosphatase activity" (GO:0008195)

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Term Information

Accession: GO:0008195
Name: phosphatidate phosphatase activity
Ontology: molecular_function
Synonyms: phosphatidate phosphohydrolase activity, 3-sn-phosphatidate phosphohydrolase activity, acid phosphatidyl phosphatase activity, phosphatic acid phosphatase activity, phosphatic acid phosphohydrolase activity, phosphatidic acid phosphatase activity
Alternate IDs: GO:0004606
Definition: Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate. Source: PMID:25814022, RHEA:27429, GOC:pr
Comment: None
History: See term history for GO:0008195 at QuickGO
Chem. react.: has participant hydrogenphosphate; has participant 1,2-diacyl-sn-glycerol; has participant 1,2-diacyl-sn-glycerol 3-phosphate(2-); has participant water
Subset: None
Related: Link to all genes and gene products annotated to phosphatidate phosphatase activity (excluding "regulates").; Link to all direct and indirect annotations to phosphatidate phosphatase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for phosphatidate phosphatase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0042578 phosphoric ester hydrolase activity
GO:0016791 phosphatase activity
GO:0042577 lipid phosphatase activity
GO:0008195 phosphatidate phosphatase activity
GO:1903741 negative regulation of phosphatidate phosphatase activity
GO:1903740 positive regulation of phosphatidate phosphatase activity
GO:1903730 regulation of phosphatidate phosphatase activity

Parents of phosphatidate phosphatase activity (GO:0008195)

subject	relation	object
phosphatidate phosphatase activity	RO:0000057	hydrogenphosphate (CHEBI:43474)
phosphatidate phosphatase activity	RO:0000057	1,2-diacyl-sn-glycerol (CHEBI:17815)
phosphatidate phosphatase activity	RO:0000057	1,2-diacyl-sn-glycerol 3-phosphate(2-) (CHEBI:58608)
phosphatidate phosphatase activity	RO:0000057	water (CHEBI:15377)
phosphatidate phosphatase activity	is_a	lipid phosphatase activity (GO:0042577)

Children of phosphatidate phosphatase activity (GO:0008195)

subject	relation	object
positive regulation of phosphatidate phosphatase activity (GO:1903740)	RO:0002213	phosphatidate phosphatase activity
negative regulation of phosphatidate phosphatase activity (GO:1903741)	RO:0002212	phosphatidate phosphatase activity
regulation of phosphatidate phosphatase activity (GO:1903730)	RO:0002211	phosphatidate phosphatase activity

EC: 3.1.3.4
MetaCyc: PHOSPHATIDATE-PHOSPHATASE-RXN
Reactome: R-HSA-2029468; R-HSA-163688; R-HSA-5221130; R-HSA-6797630; R-HSA-1483203; R-HSA-390329; R-HSA-164056; R-HSA-75899
RHEA: 27429