AmiGO 2: Term Details for "serine-type peptidase activity" (GO:0008236)

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Term Information

Accession: GO:0008236
Name: serine-type peptidase activity
Ontology: molecular_function
Synonyms: serine protease activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). Source: https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE
Comment: None
History: See term history for GO:0008236 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to serine-type peptidase activity (excluding "regulates").; Link to all direct and indirect annotations to serine-type peptidase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for serine-type peptidase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140096 catalytic activity, acting on a protein
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0017171 serine hydrolase activity
GO:0008236 serine-type peptidase activity
GO:1902572 negative regulation of serine-type peptidase activity
GO:1902573 positive regulation of serine-type peptidase activity
GO:1902571 regulation of serine-type peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0070008 serine-type exopeptidase activity
GO:1905286 serine-type peptidase complex

Parents of serine-type peptidase activity (GO:0008236)

subject	relation	object
serine-type peptidase activity	is_a	peptidase activity (GO:0008233)
serine-type peptidase activity	is_a	serine hydrolase activity (GO:0017171)

Children of serine-type peptidase activity (GO:0008236)

subject	relation	object
negative regulation of serine-type peptidase activity (GO:1902572)	RO:0002212	serine-type peptidase activity
regulation of serine-type peptidase activity (GO:1902571)	RO:0002211	serine-type peptidase activity
serine-type peptidase complex (GO:1905286)	RO:0002215	serine-type peptidase activity
serine-type endopeptidase activity (GO:0004252)	is_a	serine-type peptidase activity
positive regulation of serine-type peptidase activity (GO:1902573)	RO:0002213	serine-type peptidase activity
serine-type exopeptidase activity (GO:0070008)	is_a	serine-type peptidase activity

Reactome: R-HSA-2022383; R-HSA-1461993; R-HSA-6801766; R-HSA-9839072; R-HSA-3132753; R-HSA-9839110