Term Information

Feedback 
Accession
GO:0008278
Name
cohesin complex
Ontology
cellular_component
Synonyms
SMC/kleisin ring complex, SMC complex, cohesin core heterodimer, nuclear cohesin complex, 14S cohesin, 9S cohesin, Smc1-Smc3 complex
Alternate IDs
GO:0000798, GO:0008280, GO:0043222, GO:0008279
Definition
A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3). Source: GOC:sp, PMID:9887095, GOC:jl, GOC:vw
Comment
None
History
See term history for GO:0008278 at QuickGO
Chem. react.
None
Subset
goslim_pir
Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

Loading...
pending...
View this term in QuickGO.

Graph of GO:0008278 from QuickGO

Additional external viewing options
Additional internal viewing options
Parents of cohesin complex (GO:0008278)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cohesin complex [RO:0002215 relation] RO:0002215  sister chromatid cohesion (GO:0007062)
cohesin complex [is_a relation] is_a  protein-containing complex (GO:0032991)
cohesin complex [RO:0002162 relation] RO:0002162  cellular organisms (NCBITaxon:131567)
cohesin complex [BFO:0000050 relation] BFO:0000050  chromosome (GO:0005694)
Children of cohesin complex (GO:0008278)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
meiotic cohesin complex (GO:0030893) [is_a relation] is_a  cohesin complex
mitotic cohesin complex (GO:0030892) [is_a relation] is_a  cohesin complex
None.